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Antibiotics make way for fungal invasion in human gut
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Antibiotics are powerful for fighting infection. But they could create a dangerous imbalance in the gut, where the eradication of harmful bacteria might make room for gut fungi to invade. To find out, researchers analyzed stool samples from 14 healthy participants. Samples were collected over 3 months following a 6-day course of antibiotics. While the bacterial community mostly rebounded over those 3 months, the fungal community shifted from one characterized largely by mutually beneficial interactions (red) to one fraught with competitive interactions (blue) with half of the bacterial-fungal interactions detected before the antibiotic treatment disappearing 3 months later. Metagenomics data revealed that certain bacteria normally help keep opportunistic fungal pathogens like Candida albicans in check. Understanding how could help researchers find ways to restore balance to the gut microbiome following drug treatment or during disease..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020
Arthurian Literature and Celtic Colonization
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CC BY-NC-SA
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The course examines the earliest emergence of stories about King Arthur and the Knights of the Round Table in the context of the first wave of British Imperialism and the expanded powers of the Catholic Church during the twelfth and thirteenth centuries. The morphology of Arthurian romance will be set off against original historical documents and chronicle sources for the English conquests in Brittany, Wales, Scotland, and Ireland to understand the ways in which these new attitudes towards Empire were being mythologized. Authors will include Bede, Geoffrey of Monmouth, Chrétien de Troyes, Marie de France, Gerald of Wales, together with some lesser known works like the Perilous Graveyard, the Knight with the Sword, and Perlesvaus, or the High History of the Holy Graal. Special attention will be paid to how the narrative material of the story gets transformed according to the particular religious and political agendas of each new author.

Subject:
Arts and Humanities
English Language Arts
History
Literature
Reading Literature
World History
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Cain, James
Date Added:
02/01/2005
Biogeography, succession, and origin of the chicken intestinal mycobiome
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The gut microbial community, called the gut microbiota, plays an important role in health for both humans and animals. The bacterial members of this community are the most numerous and consequently get the most attention in research. However, there are often overlooked but important fungi, viruses, archaea, and protozoa in the microbiota too. The fungal subset of a microbiota is called the mycobiota, and it is particularly understudied in birds. To close this gap, a recent study comprehensively characterized the mycobiota of chickens bred for meat. While gut bacterial communities typically stabilize with age, the chicken mycobiota was dynamic over time with no clear pattern of successive changes and low overall diversity. The upper gastrointestinal (GI) tract mycobiota was more diverse than the lower tract mycobiota, and just 25 core fungal groups accounted for more than 85% of the fungal population in each section of the GI tract..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/18/2022
Chinua Achebe's Things Fall Apart
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CC BY
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Nigerian born Chinua Achebe is one of the world's most well-known and influential contemporary writers. His first novel, Things Fall Apart (1958), is an early narrative about the European colonization of Africa told from the point of view of the colonized people.

Subject:
Arts and Humanities
History
Literature
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
The Colonies: Motivations and Realities
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CC BY
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This collection uses primary sources to explore the motivations and realities behind life in the American colonies. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

Subject:
History
U.S. History
Material Type:
Primary Source
Provider:
Digital Public Library of America
Provider Set:
Primary Source Sets
Author:
Ella Howard
Date Added:
10/20/2015
Colonizing the Bay
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CC BY
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This lesson focuses on John Winthrop's historic "Model of Christian Charity" sermon which is often referred to by its"City on a Hill" metaphor. Through a close reading of this admittedly difficult text, students will learn how it illuminates the beliefs, goals, and programs of the Puritans. The sermon sought to inspire and to motivate the Puritans by pointing out the distance they had to travel between an ideal community and their real-world situation.

Subject:
History
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
The Conquest of America
Conditional Remix & Share Permitted
CC BY-NC-SA
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In this course the conquest and colonization of the Americas is considered, with special attention to the struggles of native peoples in Guatemala, Canada, Brazil, Panama, and colonial New England. In two segments of the course-one devoted to the Jesuit missionization of the Huron in the 1630s, the other to struggles between the government of Panama and the Kuna between 1900 and 1925-students examine primary documents such as letters, reports, and court records, to draw their own conclusions. Attention focuses on how we know about and represent past eras and other peoples, as well as on the history of struggles between native Americans and Europeans.

Subject:
Anthropology
Arts and Humanities
Cultural Geography
Ethnic Studies
History
Social Science
U.S. History
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Howe, James
Date Added:
02/01/2004
Exploration of the Americas
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CC BY
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This collection uses primary sources to explore early exploration of the Americas. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

Subject:
Ethnic Studies
History
Social Science
U.S. History
World History
Material Type:
Primary Source
Provider:
Digital Public Library of America
Provider Set:
Primary Source Sets
Author:
Kerry Dunne
Date Added:
01/20/2016
Globalization: The Good, the Bad and the In-Between
Conditional Remix & Share Permitted
CC BY-NC-SA
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This subject examines the paradoxes of contemporary globalization. Through lectures, discussions and student presentations, we will study the cultural, linguistic, social and political impact of globalization across broad international borders.
We will pay attention to the subtle interplay of history, geography, language and cultural norms that gave rise to specific ways of life. The materials for the course include fiction, nonfiction, audio pieces, maps and visual materials.

Subject:
Anthropology
Arts and Humanities
Business and Communication
Cultural Geography
Economics
History
Languages
Literature
Philosophy
Political Science
Social Science
World History
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Resnick, Margery
Terrones, Joaquín
Date Added:
09/01/2016
HIST 1301: United States History, Williams
Unrestricted Use
CC BY
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This course looks at the “big picture” of United States history. This course explores the ways in which Americans created their highly original society and culture, the stunning geographical changes that marked the early decades of our new nation, documents that reveal the evolution of key American concepts as well as the many controversies that characterized the second half of US history. One of the goals of this course is for students to come to understand the practice of historical thinking: a form of "reading" the past that you can also apply to any number of other aspects of your college work.

Subject:
History
U.S. History
Material Type:
Syllabus
Author:
Alliance for Learning in World History
Date Added:
05/01/2024
How to Stage a Revolution
Conditional Remix & Share Permitted
CC BY-NC-SA
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This course explores fundamental questions about the causes and nature of revolutions by looking at how people overthrow their rulers and establish new governments. Considers a set of major political transformations throughout the world and across centuries to understand the meaning of revolution and evaluate its impact. Examines how revolutionaries have attempted to establish their ideals and realize their goals. Asks whether radical upheavals require bloodshed, violence, or even terror. Seeks to explain why some revolutions succeed and others fail. Materials include the writings of revolutionaries, declarations and constitutions, music, films, art, novels, memoirs, and newspapers.

Subject:
Arts and Humanities
History
U.S. History
World History
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Ghachem, Malick
Ravel, Jeffrey
Wilder, Craig
Date Added:
09/01/2013
Islam, the Middle East, and the West
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CC BY-NC-SA
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This course aims to provide students with a general overview of basic themes and issues in Middle Eastern history from the rise of Islam to the present, with an emphasis on the encounters and exchanges between the “Middle East” (Southwest Asia and North Africa) and the “West” (Europe and the United States).

Subject:
Arts and Humanities
History
Social Science
World Cultures
World History
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Belli, Mériam
Date Added:
09/01/2006
Lesson 1: The Question of an American Empire
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CC BY
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This lesson will introduce the students to the challenges of American foreign policy in the late 19th century and specifically to the political debate over whether the United States should acquire further territory and/or become a European-style empire.

Subject:
History
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
Lesson 2: The Spanish-American War
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CC BY
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On April 11, 1898, two months after the battleship U.S.S. Maine was destroyed by an explosion in Havana harbor, President McKinley sent a message to Congress requesting authority to use the U.S. armed forces to end a brutal civil war in the Spanish colony of Cuba. This lesson plan, through the use of primary sources and a WebQuest Interactive, will focus on the causes of the war and the political debate in the United States over the advisability of intervening militarily in the affairs of countries.

Subject:
History
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
Lesson 3: The Matter of the Philippines
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CC BY
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The treaty of peace ending the Spanish-American War resulted in the United States obtaining the Philippine Islands from Spain. Despite intense political opposition to the acquisition of the islands, the U.S. Senate ratified the treaty. The political impact of anti-imperialist arguments, the difficult experience of suppressing native Filipino resistance, and the lack of attractive opportunities for further territorial expansion, all effectively stalled the American imperialist/expansionist movement.

Subject:
History
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
Lesson 4: Imperialism and the Open Door
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CC BY
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In 1899 and 1900, Secretary of State John Hay issued what became known as the Open Door Notes to foreign powers involved in China. Secretary Hay called on those powers to respect the rights of each other, to agree to an open market and equal trading opportunities for merchants of all nationalities, and to respect the territorial and administrative integrity of China.

Subject:
History
Material Type:
Lesson Plan
Provider:
National Endowment for the Humanities
Provider Set:
EDSITEment!
Date Added:
09/06/2019
Metabolic exchanges and viral predation guide microbial communities in deep fractured shales
Unrestricted Use
CC BY
Rating
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Deep shale formations underlie most of North America and are typically inhospitable to microbial life. However, hydrologic fracturing of shale creates space and injects moisture and nutrients into the system, thus allowing new microbial communities to form. These communities can cause problems by corroding infrastructure and souring the hydrocarbon steam. Understanding the behavior of these microbial communities could lead to better management techniques. Recently, researchers examined the microbial genomes and metabolic capacity of fractured shale wells in Oklahoma, USA. Oklahoma shale is much hotter and has lower salinity than the previously characterized formations in the eastern USA. This study found that the Oklahoma formations had greater microbial taxonomic and metabolic diversity than the eastern formations. Sampling over time revealed that this microbial community broke down complex polymers from the fracturing process and used them for nutrients..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
05/17/2022