The Pompe Predicament - Lesson One (view)

Units included with this Open Author resource:

Lesson One: Looking Through a Father's Eyes
Learning goals:
1. Describe an enzyme., 2. Explain the role of an enzyme in the human body., 3. Define gene and understand how a gene relates to a protein, 4. Explain where a lysosome is located and its role in the function of a cell, 5. Explain the genetics of Pompe disease, 6. Associate disease pathology with symptoms
Disease, pompe, translational research, Biology


A first person story is presented to the students to hook their interest in the disease. Using a jigsaw approach, students will learn about the fundamentals of Pompe disease and share information during a whole class discussion. The Pompe Predicament was developed as a part of Biomedical Explorations: Bench to Bedside which was supported by the National Center for Research Resources and the Division of Program Coordination, Planning, and Strategic Initiatives of the National Institutes of Health through Grant Number R25RR023294. Additional support provided by the University of Florida (UF) and the UF Center for Precollegiate Education and Training. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Research Resources or the National Institutes of Health.