A video from the Extreme Ice Survey in which Dr. Tad Pfeffer …
A video from the Extreme Ice Survey in which Dr. Tad Pfeffer and photographer Jim Balog discuss the dynamics of the Columbia glacier's retreat in recent years through this time-lapse movie. Key point: glacier size is being reduced not just by glacial melting but due to a shift in glacial dynamics brought on by climate change.
Students will learn about different types of breeds within the American Kennel …
Students will learn about different types of breeds within the American Kennel Club (AKC). They will determine breed and dog group differences between the major breed groups within the AKC standards.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Some proteins are central to many cell signaling processes. One of these key molecules is AKT2. An important kinase involved in cell survival, growth, and metabolism, it has ties to insulin-induced signaling and cancer. AKT2 has a critical role in immune cells such as neutrophils and macrophages; however, although AKT2 is expressed in antibody-producing immune cells called B cells, its function in B cells isn’t clear. In a recent study, researchers sought to understand the role of AKT2 in B cells using AKT2-deficient mice. They found that mice lacking AKT2 had impaired B-cell differentiation. B cells from these mice were not able to form a cluster of molecules called a signalosome in response to B-cell receptor (BCR) signaling, resulting in poor BCR signaling and impaired B cell activation and spreading. These results suggest that as a central orchestrator of signaling, AKT2 function is critical for proper BCR signaling and B cell development, ensuring a functional antibody-mediated immune response..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Gq protein-coupled receptors (GqPCRs) are membrane bound proteins that transmit signals from outside the cell to internal signaling pathways. One of these pathways is the PI3K/AKT pathway, which plays roles in cellular proliferation, survival, metabolism, and differentiation. PI3K/AKT dysregulation is also often implicated in cancers. A previous study determined that activating GqPCRs in certain cells inactivated AKT, which led to a specific type of cell death, JNK-dependent apoptosis. This unique signal seems to play an important role in physiological and pathological events like pituitary development and cardiac hypertrophy. Now, a new study determined that the mechanism of this AKT inactivation relies on another signaling-related protein, PP2A. When the GqPCRs are not activated, a fraction of PP2A "c" subunit is in a dimer complex with another protein, IGBP1 and they are bound to the p85 subunit of PI3K, causing its activation..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
ALAMOSE aims to educate undergraduate and graduate students on (i) what categories …
ALAMOSE aims to educate undergraduate and graduate students on (i) what categories of security weaknesses appear for artifacts used in DevOps, and (ii) how identified security weaknesses can be detected. ALAMOSE is funded by the U.S. National Science Foundation (NSF), and spearheaded by Akond Rahman at Auburn University. Please contact him with questions at akond@auburn.edu.
Wer war dieser Mann, der die Waffentechnik revolutionierte und doch ein gespanntes …
Wer war dieser Mann, der die Waffentechnik revolutionierte und doch ein gespanntes Verhältnis zum Krieg hatte? Diese Mini Lecture liefert einen detaillierten Einblick in Leben und Werk von Alfred Nobel.
Who was this man who revolutionized armament technology, yet had an ambivalent …
Who was this man who revolutionized armament technology, yet had an ambivalent relationship to war? This Mini Lecture provides a detailed view on the life and work of Alfred Nobel.
A continuation of MATH 2253. Topics include differentiation and integration of transcendental …
A continuation of MATH 2253. Topics include differentiation and integration of transcendental functions, integration techniques, indeterminate forms, infinite sequences and series, Taylor and Maclaurin series, parametric equations, L'Hopital's Rule, improper integrals, and polar coordinates.
Este Guia Didático surgiu como produto da Dissertação de Mestrado do Programa …
Este Guia Didático surgiu como produto da Dissertação de Mestrado do Programa de Pós-Graduação de Mestrado Profissional em Rede para o Ensino das Ciências Ambientais – PROFCIAMB, sob o Tema “APRENDENDO COM A ESCASSEZ: ALTERNATIVAS DE USO DA ÁGUA EM EIRUNEPÉ/AM” como atividade prática com os discentes do Ensino Médio do Instituto Federal de Educação, Ciência e Tecnologia do Amazonas, Campus Eirunepé sobre o abastecimento de água e como as famílias atuam na obtenção deste bem quando não fornecido adequadamente pelo Poder Público. A construção do Guia Pedagógico surgiu a partir da necessidade dos discentes compreenderem a problemática da água no mundo. Esta compreensão deve ter como marco inicial, a percepção sobre o abastecimento de água na cidade onde os mesmos moram, compreendendo as condições de captação, abastecimento e uso da água pelas suas famílias. A partir do “local” o discente será capaz de compreender o contexto da água sob o aspecto global.
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