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Protein Conservation
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In this module, students use several online databases and bioinformatics tools to study the evolutionary conservation of a protein of their choice. Students are first introduced to amino acid chemistry and to some of the theory underlying sequence comparisons. In the exercises, students:learn how amino acid side chain chemistries are reflected in the BLOSUM62 matrix used to identify conserved regions of protein sequencesuse the BLASTP algorithm to compare two homologous protein sequencesconstruct a multiple sequence alignment that compares homologous proteins from multiple speciesThis module is part of a semester-long introductory laboratory course, Investigations in Molecular Cell Biology, at Boston College. 

Subject:
Biology
Computer Science
Genetics
Material Type:
Module
Author:
Clare OConnor
Date Added:
09/03/2018