Author:
Integrated Nanosystems Development Institute (INDI)
Subject:
Biology
Material Type:
Activity/Lab
Level:
Middle School, High School
Tags:
  • DNA
  • Model
  • Nanotechnology
  • License:
    Public Domain Dedication
    Language:
    English
    Media Formats:
    Text/HTML

    Education Standards

    DNA Origami

    DNA Origami

    Overview

    This short lesson is a modeling exercise to understand the structure of DNA and its relationship to nanoscale.

    Standards

    Indiana Biology Standards: B.5.1, B.5.2, B.5.3

    Learning Objectives

    Students will construct a DNA foldable.

    Students will research the pros and cons of the synthesized DNA drug delivery system.

     

    Materials

    Downloadable Image in Color from https://www.yourgenome.org/activities/origami-dna

     

    Procedure

    After reviewing the shape and structure of DNA, students will make aDNA foldable. This link provides downloadable images in color: http://www.yourgenome.org/activities/origami-dnaShow students various images of DNA origami and explains the potential uses.

    Assign students to research the pros and cons of synthesized DNA drug delivery system in pairs, with each student taking either the pro or con side of the argument.

    Give a handout out of at least 5 acceptable websites to complete research.

    Students will then write a paragraph explaining their point of view.

    Post-lab Questions:

    1. What could be an advantage of manipulating DNA?
    2. What could be a disadvantage of manipulating DNA?

    Credits

    This learning module was created by Nicole Simpsom, a participant in Indiana University-Purdue University’s NSF-Funded “Nanotechnology Experiences for Students and Teachers (NEST)” Program (Award # 1513112).