final pretty view labelled
final stick view labelled
Flat Sticks
References
sequence
Tunnel
Wildtype
Y298C
MC1R Protein in Humans with Y298C Mutation
Overview
This contains visual material for the MC1R protein in humans, as well as visual material on the Y298C mutation in Spirit Bears.
This contains pictures, PyMOL renderings, Inkscape files, and useable content for the MC1R protein. The images show the locations of the suggested ligand binding sites, three mutations in humans that are associated with red hair (R151C, R160W, D294H), and the zoomed in version of the Y298C mutation found in Spirit bears (Ursus americanus kermodei).
There are two PyMOL renderings, one flat for ease of pointing out specific parts of the protein, one circular for a more realistic version of how the protein is shaped. Both have red residues that are the suggested ligand binding sites. The structure of the protein was based off of the following resource (Public Library of Science, 2015).
The wildtype photo is the wildtype compared to the Y298C mutation.
The Inkscape files have two versions of the same images in each. They are fully labelled with extra information.
Lastly I have added the sequence with the structure details, and also a list of references I used to make this material.