![Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain](https://oercommons.org/static/newdesign/images/materials/default-thumbnail-index.png)
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Spinal cord stimulation offers long-term relief to patients managing chronic pain, without the need for opioids. This winning combination has spurred incredible growth in the industry, with approximately 50,000 spinal cord stimulators being implanted each year and an estimated market of 7 billion U.S. dollars by 2020. But despite this progress, exactly how the technology works remains unclear. Especially with regard to potential changes in brain activity. A new review article in the journal Anesthesiology takes a closer look at these potential supraspinal pathways and actions. Covering both preclinical and clinical articles, the review starts with the 1960s, when an idea known as Gate Control Theory was proposed to explain how conventional tonic stimulation works. The theory suggests that a combination of presynaptic inhibition and inhibitory interneuronal communication occurs in the spinal cord following the electrical activation of large-diameter afferent fibers..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Applied Science
- Health, Medicine and Nursing
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 09/20/2019