Developmental dysplasia of the hip (DDH) is a one of the most common congenital abnormalities.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Hip osteoarthritis is a degenerative and painful disorder. The disease affects an estimated 21% of the population between the ages of 45 and 54, and twice that fraction among people over 75. Nearly half of cases of hip osteoarthritis can be traced to femoroacetabular impingement—the growth of extra bone over the hip joint. The progression from impingement to osteoarthritis is believed to be mediated by the release of inflammatory molecules across the hip cartilage. But the exact mechanisms are unknown. To address this gap, researchers tracked levels and patterns of inflammatory markers in cartilage from patients with symptoms of impingement. Their findings highlight the role of inflammation in upsetting joint homeostasis. The research team examined full-thickness cartilage samples gathered from the zone of impingement in 45 patients undergoing hip surgery. Reasons for surgery fell into one of three groups: early disease, late disease, or hip dysplasia..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.