Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Explain how hormones regulate the excretory systemDiscuss the role of hormones in the reproductive systemDescribe how hormones regulate metabolismExplain the role of hormones in different diseases

This patient education program explains what diabetes is, the signs and symptoms, treatment options, hyperglycemia and hypoglycemia, complications, and management of the disease. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.

This patient education program explains what diabetes is, the signs and symptoms, treatment options, hyperglycemia and hypoglycemia, complications, and management of the disease. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Diabetes is a major risk factor for myocardial infarction, stroke, and other cardiovascular diseases. The prime target for reducing cardiovascular risk is low-density lipoprotein, or LDL. LDL cholesterol has been linked to cardiovascular events in patients with type 2 diabetes. While statins have long been the primary treatment for reducing LDL, many patients are unable to reach recommended levels with a statin alone or are unable to take an effective dose. That places them at an especially high risk for cardiovascular disease. Now, a new study reports the efficacy and safety of evolocumab on top of statins in patients with both type 2 diabetes and hyperlipidemia or mixed dyslipidemia. The double-blind, phase 3 trial was conducted in patients from 10 different countries over a treatment period of 12 weeks. More than 980 patients were randomized to one of four subcutaneous treatments: 140 mg of evolocumab every 2 weeks, 420 mg of evolocumab monthly, or placebo at either of those frequencies..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This eBook is a medical education resource intended to supplement the knowledge, skills, and attitudes of medical students and pediatric residents in furthering their own knowledge about the general inpatient management of pediatric diabetes mellitus. This book may be of further use to any physician, advanced practitioners, or nurses who may also encounter pediatric patients with diabetes mellitus in the inpatient hospital setting. This book is specific to protocols and preferences for pediatric diabetes management at the University of Iowa Stead Family Children's Hospital. However, it also contains overarching concepts that transcend location wherever pediatric diabetes may be managed. At the time of publication, this book includes 4 Units, each consisting of 4-7 Chapters. Unit 1 introduces readers to an overview of diabetes mellitus, including its definition, diagnostic criteria, laboratory evaluation, clinical diagnosis, and key differences between Type 1 and Type 2 diabetes. Unit 2 dives into understanding different types of insulins and their uses. Unit 3 walks readers through the creation of initial insulin regimens for pediatric patients with new-onset diabetes. Lastly, Unit 4 dives into the details of pediatric diabetes management at Stead Family Children’s Hospitals according to the protocols and capabilities of the institution and preferences of the pediatric endocrinology division.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"In Wolfram syndrome (WFS), intracellular endoplasmic reticulum stress and reduced levels of the protein wolframin lead to diabetes and neurodegeneration. In addition, deficiency of the wolframin-encoding gene, WFS1, is known to disrupt calcium balance and change mitochondrial dynamics. Unfortunately, there is no effective treatment for WFS, but better characterization of its mechanisms might aid in therapy development. To further investigate WFS, a recent study analyzed the mRNA transcript and protein profiles in a human cell WFS model. The levels of proteins in various signaling pathways differed between the WFS cells and normal control cells. For example, proteins involved in oxidative phosphorylation, the major energy-producing pathway in mitochondria, were downregulated in the WFS cells. while proteins in other energy generation pathways were upregulated..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Type 2 diabetes is a serious disease affecting the way the body converts food into energy, and an increasing number of people are diagnosed with the disorder each year. Those whose mothers had hyperglycaemia in pregnancy (HIP) are particularly at risk, and it is possible that the microbes living in the mother’s gut may be at least somewhat responsible. To find out more, researchers compared the metabolic characteristics and gut microbial communities of mice whose mothers had HIP. The mice were born either naturally or via cesarean section and were nursed by either their own mother or a foster mouse without HIP. Cesarean section birth and foster nursing prevented the transmission of gut microbes from biological mother to offspring. In fact, the gut microbial communities of fostered offspring were more closely related to those of their foster mothers than to those of their biological mothers, with increased relative abundances of Bifidobacterium species and short-chain fatty acid bacterial metabolites..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.