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Cocaine Addiction Effects of the Brain: Binge and Craving
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Cocaine afflicts many individuals and is potently addictive. Originally hailed as a wonder-drug in the late 19th century, cocaine is now considered an illegal substance. Cocaine’s addictive properties can be attributed to changes in the dopamine reward pathway of the Ventral Tegmental Area and Substantia Nigra, Prefrontal Cortex, Dorsal Striatum, Nucleus Accumbens, Amygdala, Globus Pallidus, and Hippocampus. This drug affects the brain in two processes: binge and crave. The binge process highlights cocaine’s ability to block dopamine reuptake from the synapse resulting in hyperstimulation of the postsynaptic neuron in the dopamine reward pathway. The crave process promotes drug-seeking behavior through conditional and contextual cues. Understanding the effects of cocaine in the brain may grant insight in creating future medication and therapies to treat individuals addicted to this drug.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Simulation
Provider:
CUNY
Provider Set:
City College
Author:
Advait Apte
Anna Cahn
Ching-Jung Chen
Hysell Oviedo
Katie Cheng
Lenn Hypolite
Rafay Malik
Timmy Eng
Date Added:
06/16/2022