Conditional Remix & Share Permitted
CC BY-NC
This is about amino acids
- Subject:
- Life Science
- Material Type:
- Module
- Author:
- Mini ML
- Date Added:
- 08/25/2019
Updating search results...
2 Results
Unrestricted Use
CC BY
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition regulation in mammals. Primary bile acids are produced from cholesterol in the liver but are modified by microbes in the gut to form numerous secondary and tertiary bile acids with diverse functions. For decades, gut microbes have been known to transform bile acids through several mechanisms, including deconjugation of the amino acids glycine and taurine by bile salt hydrolases, dehydroxylation of the cholesterol core, and dehydrogenation and epimerization of the cholesterol core. Notably, alterations in the chemistry of the resulting secondary bile acids are linked to several diseases, including cirrhosis, inflammatory bowel disease, and cancer. Recently, an additional transformation mechanism was uncovered in which gut microbes conjugate amino acids to bile acids. The discovery of the resulting microbially conjugated bile acids expands the known diversity of bile acids in the mammalian gut..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
- Subject:
- Biology
- Life Science
- Material Type:
- Diagram/Illustration
- Reading
- Provider:
- Research Square
- Provider Set:
- Video Bytes
- Date Added:
- 10/13/2021