knowing anatomy of prostate, seminal vesicles and ejaculatory ducts is very important to all medical students nor only undergraduates who study basics of anatomy but also future pelvic surgeons
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Prostate cancer remains the second leading cause of cancer death in men, although the mechanisms of its progression are still debated. Extracellular vesicles are critical mediators of communication between prostate cancer cells and their surrounding cells and can influence malignancy. For example, prostasomes released from prostate cancer cells contain factors that promote cell survival and tumor progression, while large oncosomes support target cell reprogramming by delivering molecules related to cell growth, proliferation, and movement or RNA processing. Smaller exosomes can also induce reprogramming by shuttling a wide variety of proteins and nucleic acids. The numbers, cargoes, and structures of exosomes can change depending on prostate health or the cancer stage, which makes these vesicles and their contents good biomarkers, especially since they can be sampled non-invasively from body fluids. Exosomes’ ability to deliver materials to target cells can also be exploited to achieve targeted therapies..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"In 2020, approximately 191,930 people were diagnosed with prostate cancer, and an estimated 33,330 people died from the disease. The most common therapies for prostate cancer involve androgen depletion via castration and/or drug treatment. However, the relapse and mortality rates of prostate cancer remain high, prompting a need for less invasive treatments. Now, a growing number of studies suggest that prostate cancer can be inhibited by the hormone melatonin. Melatonin, which is normally associated with the regulation of sleep, can inhibit prostate cancer partly by keeping androgen receptors out of cell nuclei, thus preventing excess androgen signaling and by activating MT1 signaling, ultimately reducing levels of the prostate cancer marker prostate-specific antigen. Melatonin also reduces tumor blood vessel growth and it regulates metabolism, affects differentiation, and induces death in prostate cancer cells..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.