Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.
By the end of this section, you will be able to:Describe gel electrophoresisExplain molecular and reproductive cloningDescribe uses of biotechnology in medicine and agriculture
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Gastric cancer is one of the highest mortality cancer types, and the leading cause of gastric cancer is persistent Helicobacter pylori infection. H. pylori secretes the enzyme HtrA, which cleaves adhesion proteins like E-cadherin and allows H. pylori to cross the epithelium. Recently, researchers used proteomics to find novel targets of HtrA associated with H. pylori. They confirmed E-cadherin as a target and identified human desmoglein-2 (hDsg2), neuropilin-1, ephrin-B2, and semaphorin-4D as potential targets. hDsg2 is a component of the desmosome junctions, which play important roles in epithelial cell-to-cell adhesion. Given the importance of cell-to-cell adhesion to epithelial health, the researchers focused on hDsg2. In vitro tests confirmed that HtrA secreted by H. pylori, and not other host cell proteases, cleaved hDsg2. This study is the first to demonstrate that HtrA secreted by H. pylori directly breaks down hDsg2 and suggests that HtrA is a ‘master key’ that allows H..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.