Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Describe the four major types of lipidsExplain the role of fats in storing energyDifferentiate between saturated and unsaturated fatty acidsDescribe phospholipids and their role in cellsDefine the basic structure of a steroid and some functions of steroidsExplain the how cholesterol helps to maintain the fluid nature of the plasma membrane

By the end of this section, you will be able to:Describe the four major types of lipidsExplain the role of fats in storing energyDifferentiate between saturated and unsaturated fatty acidsDescribe phospholipids and their role in cellsDefine the basic structure of a steroid and some functions of steroidsExplain the how cholesterol helps to maintain the fluid nature of the plasma membrane

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Many metabolic diseases show clear differences in how they manifest between males and females. While gonadal steroid hormones have been suggested as the underlying cause, the gut microbiome could also play a critical role. A new study investigated how the makeup and function of the gut microbiome is related to sex, menopausal status, and circulating gonadal steroids in humans. Important differences in gut microbiota composition and functionality were found between (a) pre-menopausal women and (b) men and post-menopausal women. But obesity overrode those differences. In addition, microbiome profiles were associated with certain gonadal steroids, particularly circulating testosterone and serum progesterone. Interestingly, microbiome signatures could be transferred from human donors to microbiome-depleted male mice, with the microbiome of mice 4 weeks after transplantation predicting donors’ testosterone levels..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"More than 1 million men are diagnosed with prostate cancer each year Although effective therapies exist, resistance to androgen receptor-targeted therapy is a major challenge in managing the disease Unfortunately, the mechanisms behind therapy resistance are not yet fully understood In a recent study, researchers aimed to identify new targets for treatment against therapy-resistant prostate cancer Using gene expression analysis and 3-dimensional spheroid culture, they examined the interaction of prostate cancer (PCa) cells with cancer-associated fibroblasts (CAFs) The results showed that CAFs in the tumor environment stimulate cholesterol and steroid production in PCa cells This was mediated by pro-inflammatory, pro-migratory, and pro-angiogenic factors secreted by the CAFs, which upregulated genes involved in cholesterol synthesis Blocking cholesterol and steroid production using gene targeting or medication inhibited PCa cell growth Future studies will evaluate the mechanisms underlying the.."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.