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  • translational-research
Conditional reprogramming of pediatric airway epithelial cells
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"For the first time, scientists have figured out how to grow and extend the life of primary airway epithelial cells from newborns and young children. These cells line our nasal passages and lungs, protecting us from pathogens, and controlling our immune responses to allergens. Differences in these cells may help explain why certain infants develop wheezing and asthma later in life, but studying them has been challenging because they are difficult to obtain in babies and usually die in culture after dividing a few times. Now, researchers at Children’s National Medical Center in Washington, D.C. and George Washington University have devised a way to reprogram pediatric airway epithelial cells so that they survive, creating a new model to study respiratory disorders that take hold early in life. The team collected airway epithelial cells from 23 donors, including newborns, infants and young children..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Applied Science
Health, Medicine and Nursing
Material Type:
Research Square
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Video Bytes
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The Pompe Predicament - Lesson One
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A first person story is presented to the students to hook their interest in the disease. Using a jigsaw approach, students will learn about the fundamentals of Pompe disease and share information during a whole class discussion.

The Pompe Predicament was developed as a part of Biomedical Explorations: Bench to Bedside which was supported by the National Center for Research Resources and the Division of Program Coordination, Planning, and Strategic Initiatives of the National Institutes of Health through Grant Number R25RR023294. Additional support provided by the University of Florida (UF) and the UF Center for Precollegiate Education and Training.

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Research Resources or the National Institutes of Health.

Life Science
Material Type:
Lesson Plan
Primary Source
Teaching/Learning Strategy
Unit of Study
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