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Biology
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
08/22/2012
Biology, Genetics, Mendel's Experiments and Heredity, Characteristics and Traits
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CC BY-NC
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By the end of this section, you will be able to:Explain the relationship between genotypes and phenotypes in dominant and recessive gene systemsDevelop a Punnett square to calculate the expected proportions of genotypes and phenotypes in a monohybrid crossExplain the purpose and methods of a test crossIdentify non-Mendelian inheritance patterns such as incomplete dominance, codominance, recessive lethals, multiple alleles, and sex linkage

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Date Added:
07/10/2017
Building a better plant: Increasing nitrogen efficiency of tropical maize using multi-trait genomic prediction and selection
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Tropical maize hybrid, a single cross of flint and dent inbred lines, is an important crop throughout the Americas and Africa. Crop yield, however, is highly dependent on nitrogen availability, and fertilizers are therefore often necessary to increase production. Developing more nitrogen-efficient maize would not only cut costs for farmers, it would also increase crop yield and reduce environmental impacts. But how do you make a plant more nitrogen efficient? The performance and production of crops can be improved by selectively crossing individuals with desired traits. When such plants are crossed, they produce hybrids that are often bigger, stronger, and more vigorous than either of the parent plants. By carefully choosing which individuals are used in creating these hybrids, specific traits, such as nitrogen efficiency, can be selected for..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Botany
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/22/2022
DNA Build
Read the Fine Print
Educational Use
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
Diabetes - A Global Challenge - Translational Metabolism Part 1 (12:56)
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CC BY-NC-ND
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In this presentation we’ll translate our knowledge from genetics into clinically relevant patient stories. We’ll present case stories of translational metabolism, which means that we go from genotype to phenotype. Translational science is a multidisciplinary form of science that bridges the gap between basic science and applied science.

Course responsible: Associate Professor Signe Sørensen Torekov, MD Nicolai Wewer Albrechtsen & Professor Jens Juul Holst

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Lecture
Provider:
University of Copenhagen Department of Biomedical Science
Provider Set:
Diabetes - A Global Challenge
Author:
Assistant Professor Signe Torekov
Date Added:
01/07/2015
Don't Be a Square
Read the Fine Print
Educational Use
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After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Genetics
Conditional Remix & Share Permitted
CC BY-NC-SA
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This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subject:
Biology
Genetics
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Fink, Gerald
Kaiser, Chris
Mischke, Michelle
Samson, Leona
Date Added:
09/01/2004
Genetics Problems
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CC BY-SA
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This document contains eight genetic problems with multiple parts.  These include crosses in which only one character are studied, crosses in which two characters are studied, crosses with multiple alleles, and crosses that are sex-linked.

Subject:
Biology
Genetics
Zoology
Material Type:
Activity/Lab
Author:
Eunice Laurent
Date Added:
06/24/2022
Heredity Mix n Match
Read the Fine Print
Educational Use
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Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
09/26/2008
Identifying the genetic determinants of postoperative pain
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Going in for surgery? It’s possible the level of pain you’ll experience during recovery is encoded in your DNA. This conclusion draws from the work of an international collaboration of researchers. By looking at the outcomes of over 1000 patients, they pinpointed factors linked to ongoing postsurgical pain. They found that one important determinant is the code of a single gene – the brain-derived neurotrophic factor, or BDNF, gene – opening new avenues for how we understand, and treat, chronic pain. Nearly all surgical patients experience some degree of postoperative pain, but it’s usually resolved as they heal. For many, however, it can last for months or even years – a condition referred to as chronic postsurgical pain. Although some elements that lead to this condition are known – nerve injury during surgery, for example, is one common cause – there’s often no easily identifiable culprit. Enter genetics..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/23/2019
Modi-FLIED
Conditional Remix & Share Permitted
CC BY-NC
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Students will breed fruit flies through several generations and record their data using mathematical models in order to demonstrate the inheritance of trait variations.

Subject:
Algebra
Genetics
Life Science
Mathematics
Measurement and Data
Numbers and Operations
Ratios and Proportions
Material Type:
Unit of Study
Provider:
Lane County STEM Hub
Provider Set:
Content in Context SuperLessons
Author:
Courtney Stitt
Jessica Johnson
Date Added:
06/27/2017
Pre-7.01: Getting up to Speed in Biology
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CC BY-NC-SA
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This self-paced course was originally designed to help prepare incoming MIT students for their first Introductory Biology Course (known at MIT as 7.01). It will also be useful for anyone preparing to take an equivalent college-level introductory biology class elsewhere. It includes lecture videos, interactive exercises, problem sets, and one exam.  Lecture Topics: Molecules of Life, The Cell and How it Works, Information Transfer in Biology, Inheritance and Genetics, and Building with DNA.
Go to OCW’s Open Learning Library site for Pre-7.01: Getting up to Speed in Biology. The site is free to use, just like all OCW sites. You have the option to sign up and enroll in the course if you want to track your progress, or you can view and use all the materials without enrolling.

Subject:
Biology
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Ray, Diviya
Sive, Hazel
Date Added:
06/01/2019
Psychology
Unrestricted Use
CC BY
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Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

Subject:
Psychology
Social Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
02/14/2014
Psychology, Biopsychology, Human Genetics
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Explain the basic principles of the theory of evolution by natural selectionDescribe the differences between genotype and phenotypeDiscuss how gene-environment interactions are critical for expression of physical and psychological characteristics

Subject:
Psychology
Social Science
Material Type:
Module
Date Added:
07/10/2017
Soil and plant genotype shape microbial communities in model legume
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Plants form a close bond with a vast range of microorganisms. In fact, this microbiome could be viewed as an extended phenotype of the plant genome enhancing plants’ ability to cope with environmental stress. To understand this connection, researchers recently examined the microbiome of the model legume Medicago truncatula. They found that bacterial diversity decreased between external and internal plant compartments and that microbiome composition was shaped by strong interactions between compartment type, soil, and plant genotype with the microbial composition of external compartments driven by soil origin and the microbial composition of internal compartments driven by host genetics. All compartments were dominated by Ensifer, the nitrogen-fixing bacteria that form root nodule symbiosis with M. truncatula..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020
Unraveling the genetic risk factors for Alzheimer’s disease
Unrestricted Use
CC BY
Rating
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The strongest genetic risk factor for Alzheimer’s disease may impair the body’s cellular recycling system, allowing the build-up of harmful byproducts in the brain. People carrying the gene variant known as APOE4 are at an increased risk for the early development of Alzheimer’s and show high numbers of the brain plaques characteristic of the disease. But the underlying reason for this effect isn’t clear. Now, researchers have shown that APOE4 interferes with autophagy -- the body’s way of recycling unneeded or harmful cellular material – providing new insights into how and why APOE4 conveys such a strong risk for Alzheimer’s. The team looked at the relationship between APOE4 and a protein known as TFEB, considered a master regulator of autophagy-related genes. Prior studies have linked reduced TFEB expression to the presence of amyloid-beta plaques in the brain..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Applied Science
Health, Medicine and Nursing
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
09/20/2019