This guide takes the reader through the 3D Printing for Repair (3DP4R) process. It consists of guidelines and tools to create a 3D printable version of spare parts needed for a product repair. 3D printing a spare part is more than just printing the original part. Instead, it is an iterative process in which the part is analysed, redesigned, manufactured, and tested, in order to come to a final part. This guide will describe these four phases in detail. The guide is meant for anybody who is interested in trying to manufacture spare parts with 3D printing technologies, remakers, tinkerers, volunteer repairers, professional repairers, and everyone who is interested in repair initiatives.

This is a clinically oriented course, which covers topics that were not included in the basic courses of both removable partial denture fabrication and complete denture fabrication. Topics including denture repairs, overdentures, implant supported dentures, single dentures, and combination case will be covered on the complete denture side of the course. Topics on the removable partial denture side of the course will include rotational path removable partial dentures, swing lock and precision attachment removable partial dentures, as well as repair and maintenance phase information.

Students use a tension-compression machine (or an alternative bone-breaking setup) to see how different bones fracture differently and with different amounts of force, depending on their body locations. Teams determine bone mass and volume, calculate bone density, and predict fracture force. Then they each test a small animal bone (chicken, turkey, cat) to failure, examining the break to analyze the fracture type. Groups conduct research about biomedical challenges, materials and repair methods, and design repair treatment plans specific to their bones and fracture types, presenting their design recommendations to the class.

Students learn about the role engineers and engineering play in repairing severe bone fractures. They acquire knowledge about the design and development of implant rods, pins, plates, screws and bone grafts. They learn about materials science, biocompatibility and minimally-invasive surgery.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"One of the biggest challenges in orthopedic surgery are deep osteochondral defects in the knee arising from adolescent osteochondritis dissecans or spontaneous osteonecrosis. Many surgical techniques can help manage these conditions, but those yielding the best results aren’t clear. One promising option is transplantation of a patient’s own bone tissue or cartilage cells to a site of injury. Researchers have now compared two such transplantation techniques – autologous bone grafting and the autologous chondrocyte implantation “sandwich” technique – to understand how to best help knee tissue heal. Both methods start much like how a dental cavity is treated. First, a high-speed bur is used to remove injured bone until healthy bone is reached. In autologous bone grafting, the defect is then packed with a patients’ own bone chips, and the graft surface is secured with sutures if needed. These steps are performed while a tourniquet is applied to the leg..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Students learn how forces affect the human skeletal system through fractures and why certain bones are more likely to break than others depending on their design and use in the body. They learn how engineers and doctors collaborate to design effective treatments with consideration for the location, fracture severity and patient age, as well as the use of biocompatible materials. Learning the lesson content prepares students for the associated activity in which they test small animal bones to failure and then design treatment repair plans.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Sepsis is a life-threatening overreaction of the immune system to infection. Sepsis causes damage to vascular endothelial cells, which play an important role in maintaining vascular function. Treatment strategies that restore vascular endothelial cell function after sepsis are desperately needed. Pericyte-derived microvesicles (PMVs) have had therapeutic effects in other disorders and may be useful in sepsis treatment. To evaluate the potential treatment utility of PMVs, researchers combined experiments in rats and cultured vascular endothelial cells. PMVs were able to protect lung tissue and improve pulmonary function of septic rats. PMVs were also protective of cellular function in the cell culture model. Through subsequent experiments, the researchers determined that PMV absorption was mediated by the cell-surface protein CD44. and that PMVs restored vascular function by delivering the signaling molecule CTGF and activating the ERK1/2- STAT3 pathway..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Students learn about how biomedical engineers aid doctors in repairing severely broken bones. They learn about using pins, plates, rods and screws to repair fractures. They do this by designing, creating and testing their own prototype devices to repair broken turkey bones.

Over several days, students learn about composites, including carbon-fiber-reinforced polymers, and their applications in modern life. This prepares students to be able to put data from an associated statistical analysis activity into context as they conduct meticulous statistical analyses to evaluate/determine the effectiveness of carbon fiber patches to repair steel. This lesson and its associated activity are suitable for use during the last six weeks of an AP Statistics course; see the topics and timing note for details. A PowerPoint® presentation and post-quiz are provided.

In this activity, students will be able to practice talking about technology. Students will also be able to practice talking to an employee to determine how to fix their product or obtaining a new one.

In this activity, students will be able to practice talking about technology. Students will also be able to practice talking to an employee to determine how to fix their product or obtaining a new one.

In this activity, students will be able to practice talking about technology. Students will also be able to practice talking to an employee to determine how to fix their product or obtaining a new one.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The root of the medial meniscus is a vital component that provides stability and cushions axial loads to protect the knee. For that reason, meniscal root tears can be especially debilitating; studies have shown that tearing the posterior root of the medial meniscus is functionally and biomechanically comparable to a complete meniscectomy. Historically, such tears were treated without surgery or with partial removal of the meniscus. Now, clinicians are shifting toward preserving the biomechanical function of the medial meniscus through root repair. While good outcomes have been reported for this surgical treatment option, relatively few studies have compared root repair with other treatment methods. Authors of a recent study compared the long-term outcomes of nonoperative management or partial meniscectomy with those of root repair by the transtibial pull-through technique..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

In this activity, students will practice discussing technology. Students will also practice talking to an employee to determine how to fix their product or obtain a new one.

In this activity, students will discuss technology. Students will also practice interacting with an employee to determine how to fix their product or obtain a new one.

In this activity, students will discuss technology. Students will also practice interacting with an employee to determine how to fix their product or obtain a new one.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"RNA base-editing tools enable scientists to study gene function and develop treatments for genetic diseases. The pioneering tool REPAIR changes A bases into I bases, while the newer RESCUE system changes A and C bases into I and U bases, respectively. However, both systems tend to edit unintended, or off-target, sites in addition to desired sites. To enable more precise RNA editing, researchers recently designed a new system, ecRESCUE, by fusing the destabilization domain (DD) of the E. coli protein ecDHFR to the RESCUE system. The DD degrades the two RESCUE proteins (dRanCas13b and ADAR2) unless the drug TMP is present, making the system drug-inducible. In vitro, ecRESCUE was just as effective as RESCUE in the presence of TMP, but ecRESCUE-mediated editing was greatly reduced in the absence of TMP. When 3 specific sites were targeted, TMP-induced ecRESCUE made many fewer off-target edits than RESCUE..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.