This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"(Pro)renin receptor, or (P)RR, is a cell receptor expressed throughout the body. Historically, knowledge about (P)RR has been limited to its functions in the heart and kidneys. But now, growing evidence suggests (P)RR plays a major role in various cancers. Over the last 5 years, researchers have discovered that certain cancers produce abnormally high amounts of (P)RR . which can trigger the formation of tumors in the pancreas, colon, and brain. A recently published review outlines the numerous newly recognized roles of (P)RR in cancer. as well as ways that (P)RR can be used against cancer. including as a target for monoclonal antibody therapy. To read the full review, visit biosignaling.biomedcentral..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

By the end of this section, you will be able to:Explain why classification systems are necessary in the study of psychopathologyDescribe the basic features of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)Discuss changes in the DSM over time, including criticisms of the current editionIdentify which disorders are generally the most common

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"With the COVID-19 pandemic causing a global health crisis, accurate diagnosis is critical. Diagnosing acute disease relies on RT-PCR tests measuring the presence of SARS-CoV-2 in the sampled material but in patients with suspected COVID-19 with a negative RT-PCR result, measuring anti-viral antibodies can help clinicians identify infected individuals. Antibody testing can also determine if someone was previously infected and help to measure the prevalence of the virus in a community. A new study characterizes an assay measuring total antibodies – combined IgA, IgM, and IgG isotypes – against SARS-CoV-2. The assay, ECLIA, specifically measures antibodies against the S1 subunit of the viral spike, which carries the virus’s receptor binding domain. Researchers in Liechtenstein evaluated ECLIA in a population with 125 cases of confirmed SARS-CoV-2 infection and 1159 individuals without evidence of COVID-19. The results showed a test sensitivity of 97.6%, while the specificity was 99.8%..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Requests for medical imaging and radiologist reports are on the rise in hospital emergency departments. The increase in demand has raised concerns regarding x-ray image interpretation, resulting in longer turnaround times. To maintain a high standard of patient care, researchers suggest that radiographers provide an initial opinion of images using a clear system to quickly communicate these findings with the medical team. Radiographer Preliminary Image Evaluation, or PIE, is an Australian system that complements the radiologist’s report. A PIE can assist an emergency referrer in their diagnosis more quickly when the radiologist’s report is delayed reducing the likelihood of a missed abnormality on medical images. The study concluded that radiographers operate at a relatively high accuracy with PIE in place potentially improving emergency care service for patients..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Bladder cancer is the 10th most frequent malignancy in the world. Despite the availability of several treatment options, including surgery, chemotherapy, and radiotherapy, outcomes for patients with bladder cancer remain poor. Fortunately, a growing understanding of the molecular origins of the disease is revealing new targets for treatment. Among the most promising are a family of enzymes called tyrosine kinases. Tyrosine kinases modify the structure and function of tyrosine-containing proteins. This action helps regulate cellular processes such as growth, migration, differentiation, and metabolism. Dysregulation of tyrosine kinases is part of the pathway that leads to signs and symptoms of bladder cancer. Abnormal tyrosine kinase function can be caused by mutations, amplification, and chromosomal abnormalities. Ongoing studies are discovering how tyrosine kinases can serve as early markers of bladder cancer and how they might be manipulated to stop the progression of bladder tumors..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Tiny but tenacious, the tick is one of the most dangerous creatures on earth—and perhaps one of the most misunderstood. Because while typically associated with Lyme disease, ticks can actually harbor more than 120 different species of bacteria, each a unique source of infection. Unfortunately, the one-microbe, one-disease myth surrounding the tick extends well beyond the court of public opinion. The lack of broad-spectrum diagnostics in the clinic means that a single sufferer of tick-borne disease may spend up to $60,000, or 54,000 €, on more than 11 visits, doctors, and tests just to get a proper diagnosis. A 2018 blood analysis of 432 individuals showing symptoms of Lyme disease puts the problem in perspective—and calls for revamped screening procedures that decrease the probability of missed or misdiagnosis..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Stroke is the third largest cause of death in the UK after heart disease and cancer. It is also the single leading cause of severe disability in the UK. Classification of stroke is crucial in planning treatment and is a good indication of prognosis

This Learning Object helps individuals understand how to make the diagnosis of stroke using the Oxford Stroke classification. It is suitable for any health care professionals involved in the management of stroke but especially doctors and medical students

OBJECTIVES:
* To develop an understanding of the different symptoms and signs seen in stroke
* To be able to classify the type of stroke using the Oxford Stroke classification
* To relate the clinical diagnosis to the likely anatomical lesion and pathology
* To understand the importance of the clinical classification in estimating prognosis

Please note that all persons were filmed with their consent.

Anchoring Phenomenon: Identical twins have the same DNA yet one was diagnosed with breast cancer and the other was not?? One about diabetes? Unit Essential Question: Why are some people diagnosed with diabetes and breast cancer while others are not?

Students are introduced to the concepts of the challenge question. First independently, and then in small groups, they generate ideas for solving the grand challenge introduced in the associated lesson: Your grandmother has a fractured hip and a BMD of -3.3. What medical diagnosis explains her condition? What are some possible causes? What are preventative measures for other family members? Students complete a worksheet that contains the pertinent questions, as well as develop additional questions of their own, all with the focus on determining what additional background knowledge they need to research. Finally, as a class, students compile their ideas, resulting in a visual as a learning supplement.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A new diagnostic algorithm could lead to earlier and more accurate diagnosis of paroxysmal nocturnal hemoglobinuria, a life-threatening hematopoietic stem cell disorder. Early diagnosis of PNH is essential to avoid serious, potentially fatal outcomes, but timely identification is complicated by the condition’s rarity and the non-specificity of the attendant symptoms. To address this gap, a committee of PNH experts developed an algorithm for screening and diagnosis based on consensus from physicians with real-world experience in treating the disorder. The result should help non-specialists derive an appropriate differential diagnosis. A handful of core signs and symptoms form the foundation of the algorithm. These include symptoms of anemia, such as fatigue, tachycardia, shortness of breath, and headache; thrombotic events; dark-colored urine; intermittent abdominal pain; esophageal spasms; and dysphagia..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

In this activity, students will have the opportunity to learn about medicine in Japan. Students will also determine what medicine to give to people based on their symptoms.