Sal reflects on the amazing speed and precision with which DNA replication takes place.

These supplemental activities are intended to introduce students to classic and modern experiments in Cell Biology and Genetics. All of these activities are Open Educational Resources.

This course will introduce you to a general overview of the biological world. Important concepts will be reinforced and expanded upon through completion of weekly laboratory activities and homework assignments. Upon successful conclusion of the course, students will be able to do the following: Describe the nature of science, including its methods and its limitations; Describe the basic methodology of doing science and the scientific method; Use the scientific method to study everyday situations as well as in laboratory/field investigations; Identify, describe, and explain at a rudimentary level and present examples of, the characteristics common to all living things; Explain that living organisms are composed of molecules which interact in a variety of different chemical reactions necessary to sustain life; Explain that living organisms are comprised of one or more cells and are classified as prokaryotic or eukaryotic based on cellular characteristics; Describe the hereditary information possessed by living and explain how that information determines the cellular characteristics and functions (including basic Mendelian genetics); Explain and describe, with examples, the diversity of life, at different levels (basic molecular to ecological) and how it is hierarchically organized into systems; Explain how evolution by natural selection occurs, and describe the evidence that supports the theory of evolution; and more.

This unit plan is designed to spark students’ interest in critical thinking and scientific discovery. This unit is based on the book, “Survival of the Sickest: A medical maverick discovers why we need disease” by Jonathan Prince and Sharon Moalem. The book explores the evolution of different diseases throughout its eight chapters. The lesson plan is designed to take about 21 days (50-minute class periods). For this book, the class reads the Prologue together. Then, groups of students are assigned a chapter that they will teach to the class. Their teaching will include a presentation, activity, and facilitated discussion. (The unit plan helps the students learn how to do each of these tasks.) A final project is included at the end of the unit - a book review of the entire book.  The summative grade for this unit is multi-part - the teaching assignment and the book review. Three quizzes are included, which would also be small summative grades. The notes packets and teaching planning sheets are all formative grades. A team member peer review is another part of the project. 

Syllabus for course at Western Oregon University that outlines course goals and program outcomes and includes a schedule with weekly topics and reading. Included reading assignments come from the open access textbook "Introduction to Genetics" (Singh et al, 2023) available at https://opengenetics.pressbooks.tru.ca.

In this activity, students will create a segment of DNA out of wire and play-doh.  Using a simple computer code, they will make their DNA talk by connecting a Makey Makey circuit board and hooking it up to a computer.

This activity uses DNA sequences, protein sequence, and chromosome-density maps to re-trace the ancestry of humans and some of their closest relatives.

This is a handout which includes an assignment based on the topic of teratogen's exposure during pregnancy. This  information has the purpose to create awareness to a pregnant woman about the harm her baby is experiencing in the womb when exposed to toxic substances.  The letter is written from the baby's experience. Through this assignment, students will give voice to an unborn baby. They will assess two students' letters by completing two peer reviews

Thomas Hunt Morgan's pioneering fruit fly work that helped validate the chromosomal theory of inheritance.

How is it that all cells in our body have the same genes, yet cells in different tissues express different genes? A basic notion in biology that most high school students fail to conceptualize is the fact that all cells in the animal or human body contain the same DNA, yet different cells in different tissues express, on the one hand, a set of common genes, and on the other, express another set of genes that vary depending on the type of tissue and the stage of development. In this video lesson, the student will be reminded that genes in a cell/tissue are expressed when certain conditions in the nucleus are met. Interestingly, the system utilized by the cell to ensure tissue specific gene expression is rather simple. Among other factors - all discussed fully in the lesson - the cells make use of a tiny scaffold known as the “Nuclear Matrix or Nucleo-Skeleton”. This video lesson spans 20 minutes and provides 5 exercises for students to work out in groups and in consultation with their classroom teacher. The entire duration of the video demonstration and exercises should take about 45-50 minutes, or equivalent to one classroom session. There are no supplies needed for students’ participation in the provided exercises. They will only need their notebooks and pens. However, the teacher may wish to emulate the demonstrations used in the video lesson by the presenter and in this case simple material can be used as those used in the video. These include play dough, pencils, rubber bands (to construct the nuclear matrix model), a tennis ball and 2-3 Meters worth of shoe laces. The students should be aware of basic information about DNA folding in the nucleus, DNA replication, gene transcription, translation and protein synthesis.

The trp operon is a well-studied operon when it comes to gene regulation. It is involved in the biosynthesis of the amino acid tryptophan.

Understanding Biodiversity presents an overview of biodiversity, its importance and relevance to humans, all living things, and the Earth. It includes species pages and a template to engage and involve students in real-life data collection.

This laboratory manual is intended for use in a biology laboratory course taken by non-science majors, pre-biology, and pre-allied health majors.

Laboratory exercises provide students with experience in basic laboratory skills, gathering and organizing data, measuring and calculating, hypothesis testing, analysis of data, writing, and laboratory safety. The skill sets are designed to promote the development of critical thought and analysis. Students work with living and preserved specimens, and laboratory reagents and equipment.

it would be ideal if students already have learned that DNA is the genetic material, and that DNA is made up of As, Ts, Gs, and Cs. It also would help if students already know that each human has two versions of every piece of DNA in their genome, one from mom and one from dad. The lesson will take about one class period, with roughly 30 minutes of footage and 30 minutes of activities.

Using a literature review and primary sources that were part of the review, students examine data to evaluate if this data can predict future life choices. Students will learn content in Math, Biology and Language Arts during this literacy-based lesson that supports students in using textual evidence to develop and support claims.

In this activity students examine karyotypes from five individuals to try to identify which chromosomes determine gender in humans. This activity is also a good illustration of meiotic non-disjunction.

In a class discussion format, the teacher presents background information about basic human genetics. The number of chromosomes in both body cells and egg and sperm cells is covered, as well as the concept of dominant and recessive alleles. Students determine whether or not they possess the dominant allele for the tongue-rolling gene as an example.

An interview with biologist Gro Amdam, one of the members of the group that brought us the bee genome. Hey just what is a genome and could bees hold the answer to aging? In this show we learn the answers to these questions and why researchers are buzzing around bees.

Students use DNA profiling to determine who robbed a bank. After they learn how the FBI's Combined DNA Index System (CODIS) is used to match crime scene DNA with tissue sample DNA, students use CODIS principles and sample DNA fragments to determine which of three suspects matches evidence obtain at a crime location. They communicate their results as if they were biomedical engineers reporting to a police crime scene investigation.