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New model describes role of key protein in translational reprogramming
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Cold shock domain containing E1, or CSDE1, is emerging as a powerful protein in the cell. Growing evidence suggests that CSDE1 reprograms how RNA codes are ultimately translated into proteins, which means CSDE1 could be pivotal in how cells respond to internal and external changes like those brought on by disease. In a new review, researchers outline a model that could explain CSDE1’s reprogramming ability. According to the model, CSDE1 acts as a connector between RNAs and the specific proteins capable of regulating or altering those RNAs. For regulating proteins that can’t normally bind to RNAs, CSDE1 provides a bridge between the two. For proteins that do bind to RNAs, CSDE1 enhances that connection, and for proteins that can but don’t typically bind to certain RNAs, CSDE1 reshapes those RNAs to make binding possible. How CSDE1 connects proteins to RNAs in response to stress isn’t yet clear, but equipped with this new model, researchers could begin to understand CSDE1’s role in human disease..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/27/2020
Open Anthology of Early World Literature in English Translation
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CC BY-NC-SA
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A collection of free and open primary texts in digital formats for the study of early world literature in English translation. Multiple English translations are provided for comparison and study, as well as open secondary and supplemental resources.

Subject:
Arts and Humanities
Literature
Material Type:
Textbook
Provider:
University System of Georgia
Provider Set:
Galileo Open Learning Materials
Author:
Japeth Koech
Susan Hrach
Date Added:
03/20/2015
PIWI-interacting RNAs are promising biomarkers for targeting glioma and other cancers
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Glioma is the most common primary brain tumor and represents a major health problem across the globe. Understanding how gliomas form has proven difficult, especially at the molecular level, but growing evidence points to the important roles played by non-coding RNAs, especially small non-coding RNAs that interact with PIWI proteins, or piRNAs. piRNAs execute functions associated with epigenetic reprogramming and can regulate transcription, translation, development, and mRNA stability. In fact, piRNAs have been detected in many types of cancer and are known to be involved in the development and spread of certain tumors. piRNAs are formed either through the “primary processing pathway” or the secondary “ping-pong cycle” pathway. In conjunction with PIWI proteins, piRNAs execute epigenetic regulation of genes by modifying histones. In this way, piRNAs can influence numerous molecular signaling pathways associated with the formation and spread of gliomas, including the PI3K/AKT and TNF signaling pathways..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/12/2020
PhET Simulation: Estimation
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CC BY
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This interactive Flash animation allows students to explore size estimation in one, two and three dimensions. Multiple levels of difficulty allow for progressive skill improvement. In the simplest level, users estimate the number of small line segments that can fit into a larger line segment. Intermediate and advanced levels offer feature games that explore area of rectangles and circles, and volume of spheres and cubes. Related lesson plans and student guides are available for middle school and high school classroom instruction. Editor's Note: When the linear dimensions of an object change by some factor, its area and volume change disproportionately: area in proportion to the square of the factor and volume in proportion to its cube. This concept is the subject of entrenched misconception among many adults. This game-like simulation allows kids to use spatial reasoning, rather than formulas, to construct geometric sense of area and volume. This is part of a larger collection developed by the Physics Education Technology project (PhET).

Subject:
Applied Science
Education
Mathematics
Physical Science
Physics
Technology
Material Type:
Activity/Lab
Interactive
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Michael Dubson
Mindy Gratny
Date Added:
01/22/2006
Poetry in Translation
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CC BY-NC-SA
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This seminar addresses the inherent challenges of translating poetry from different languages, cultures, and eras. Students do some translation of their own, though accommodations are made if a student lacks even a basic knowledge of any foreign language.

Subject:
Arts and Humanities
English Language Arts
Literature
Reading Literature
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Asarina, Alevtina
Custer, David
Date Added:
02/01/2006
Prizewinners
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CC BY-NC-SA
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This 6-unit subject gives students the opportunity to immerse themselves in the poetry of two living Nobel Laureates: the Caribbean poet, Derek Walcott, and the Northern-Irish poet, Seamus Heaney. We will begin and end the semester with their magnificent epic works: Heaney’s translation of the Anglo-Saxon epic Beowulf, and Walcott’s Omeros (a modern epic set in the West Indies). Between these major narrative poems, we will read a rich selection of their shorter poems, as well as some of their reflections in prose on what poetry does, on what other poets do, and what it means to write in English from the historical and political situation of Northern Ireland (for Heaney) or the Caribbean (for Walcott).

Subject:
Arts and Humanities
English Language Arts
Literature
Reading Literature
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Fuller, Mary
Date Added:
02/01/2007
Put yourself in the graph
Unrestricted Use
CC BY
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Putting a graph on the floor using painters tape students practice translation, rotation, reflection,dilation, by doing these concepts to themselves while standing in the graph.

Subject:
Mathematics
Material Type:
Interactive
Lesson Plan
Simulation
Date Added:
09/29/2015
The Quadratic Equation: It's Hip to be Squared
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CC BY-NC-SA
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Video lecture on quadratic equations and their graphs. The video connects the equation, the graph, the roots, and the minimum or maximum of the quadratic function.

Subject:
Mathematics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Date Added:
07/12/2014
Qur'an
Read the Fine Print
Educational Use
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This website includes the entire Qur'an in Arabic and is translated into more than 30 languages. Users can select which chapter they'd like to view and can also search for words and phrases in multiple languages; for English, six different translations are available, as is a transliteration of the Qur'an to aid in reading. The tafsir of al-Jalalain is on the website in Arabic as well. An audio component is also available.

Subject:
Arts and Humanities
Languages
Material Type:
Reading
Provider:
Quran
Date Added:
10/14/2013
A Recipe for Protein Production.docx
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CC BY
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The activity is designed to teach the protein production steps by putting the students into the processes by becoming DNA triplets, RNA codons, and transfer RNA.

Subject:
Life Science
Material Type:
Activity/Lab
Author:
Janet Bouknight Bargar
Date Added:
06/26/2018
Studio Seminar in Public Art
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CC BY-NC-SA
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How do we define Public Art? This course focuses on the production of projects for public places. Public Art is a concept that is in constant discussion and revision, as much as the evolution and transformation of public spaces and cities are. Monuments are repositories of memory and historical presences with the expectation of being permanent. Public interventions are created not to impose and be temporary, but as forms intended to activate discourse and discussion. Considering the concept of a museum as a public device and how they are searching for new ways of avoiding generic identities, we will deal with the concept of the personal imaginary museum. It should be considered as a point of departure to propose a personal individual construction based on the concept of defining a personal imaginary museum - concept, program, collection, events, architecture, public diffusion, etc.

Subject:
Applied Science
Architecture and Design
Art History
Arts and Humanities
Visual Arts
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Muntadas, Antonio
Date Added:
02/01/2006
Symmetry, Structure, and Tensor Properties of Materials
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CC BY-NC-SA
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This course covers the derivation of symmetry theory; lattices, point groups, space groups, and their properties; use of symmetry in tensor representation of crystal properties, including anisotropy and representation surfaces; and applications to piezoelectricity and elasticity.

Subject:
Applied Science
Engineering
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Wuensch, Bernhardt
Date Added:
09/01/2005
Topics in Computational and Systems Biology
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CC BY-NC-SA
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This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments.
The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB Ph.D. program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology.

Subject:
Applied Science
Biology
Engineering
Life Science
Physical Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Burge, Christopher
Gilbert, Wendy
Gore, Jeff
Tidor, Bruce
White, Forest
Date Added:
09/01/2010
Topics in Modern French Literature and Culture: North America Through French Eyes
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CC BY-NC-SA
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This course offers an analysis of the keen interest shown by France and the French in North American cultures since the eighteenth century. Not only did France contribute to the construction of both Canadian and American nations but also it has constantly delineated its identity by way of praising or criticizing North American cultures. Taught in French.

Subject:
Anthropology
Arts and Humanities
English Language Arts
Languages
Literature
Reading Literature
Social Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
MIT OpenCourseWare
Author:
Perreau, Bruno
Date Added:
02/01/2014
Translating for Canada, eh? (version 2)
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CC BY-NC-SA
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Do you need to translate for a Canadian audience? We’ve got you covered! This ebook briefly introduces the concepts of translation and localization and then presents a range of free online tools and resources, including term banks, bilingual concordancers, tools for comparing language varieties, machine translation tools, ChatGPT, and language portals. In each case, the tools and resources that are presented have a distinctly Canadian flavour to help translators to localize texts into Canadian English and Canadian French. For each tool or resource, there is a short practical exercise to get you started. What are you waiting for, eh? (This version supersedes version 1.0: https://oercommons.org/courses/translating-for-canada-eh)

Subject:
Arts and Humanities
Languages
Material Type:
Textbook
Provider:
eCampusOntario
Author:
Lynne Bowker
Date Added:
01/16/2024
Translation Exercises (Youtube Channel)
Read the Fine Print
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This video series consists of 5 videos in which the instructor (from the Sibaway Institute) goes through two traditional proverbs, word by word, and translates them. He explains and references several Arabic and English grammatical concepts while doing so, attempting to teach both translation skills and grammar at the same time.

Subject:
Arts and Humanities
English Language Arts
Language, Grammar and Vocabulary
Languages
World Cultures
Material Type:
Lecture
Provider:
Sibaway Institute for Arabic and Quranic Studies
Date Added:
10/14/2013
A brief journey through Arabic grammar: Part 2
Read the Fine Print
Educational Use
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This is the second part of a tutorial on the very basics of Arabic grammar. Using vocabulary built on the Qur'an and the hadith, the tutorial uses vocabulary lists and translation exercises to teach grammatical points. The answers are included in the exercises. Grammar covered in the second half includes subjects, objects, verbs, verb tenses and conjugations, passive and active voice, imperatives, masdars, passive and active participles, the ten measures of the Arabic verb, pronouns attached to verbs, and some final notes on the idaafa, plurals, and translation in general.

Subject:
Arts and Humanities
Languages
Material Type:
Reading
Provider:
eMuslim
Date Added:
10/14/2013