Background: The reproducibility policy at the journal Biostatistics rewards articles with badges for data and code sharing. This study investigates the effect of badges at increasing reproducible research. Methods: The setting of this observational study is the Biostatistics and Statistics in Medicine (control journal) online research archives. The data consisted of 240 randomly sampled articles from 2006 to 2013 (30 articles per year) per journal. Data analyses included: plotting probability of data and code sharing by article submission date, and Bayesian logistic regression modelling. Results: The probability of data sharing was higher at Biostatistics than the control journal but the probability of code sharing was comparable for both journals. The probability of data sharing increased by 3.9 times (95% credible interval: 1.5 to 8.44 times, p-value probability that sharing increased: 0.998) after badges were introduced at Biostatistics. On an absolute scale, this difference was only a 7.6% increase in data sharing (95% CI: 2 to 15%, p-value: 0.998). Badges did not have an impact on code sharing at the journal (mean increase: 1 time, 95% credible interval: 0.03 to 3.58 times, p-value probability that sharing increased: 0.378). 64% of articles at Biostatistics that provide data/code had broken links, and at Statistics in Medicine, 40%; assuming these links worked only slightly changed the effect of badges on data (mean increase: 6.7%, 95% CI: 0.0% to 17.0%, p-value: 0.974) and on code (mean increase: -2%, 95% CI: -10.0 to 7.0%, p-value: 0.286). Conclusions: The effect of badges at Biostatistics was a 7.6% increase in the data sharing rate, 5 times less than the effect of badges at Psychological Science. Though badges at Biostatistics did not impact code sharing, and had a moderate effect on data sharing, badges are an interesting step that journals are taking to incentivise and promote reproducible research.

Beginning January 2014, Psychological Science gave authors the opportunity to signal open data and materials if they qualified for badges that accompanied published articles. Before badges, less than 3% of Psychological Science articles reported open data. After badges, 23% reported open data, with an accelerating trend; 39% reported open data in the first half of 2015, an increase of more than an order of magnitude from baseline. There was no change over time in the low rates of data sharing among comparison journals. Moreover, reporting openness does not guarantee openness. When badges were earned, reportedly available data were more likely to be actually available, correct, usable, and complete than when badges were not earned. Open materials also increased to a weaker degree, and there was more variability among comparison journals. Badges are simple, effective signals to promote open practices and improve preservation of data and materials by using independent repositories.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Alzheimer’s disease (AD) is the leading cause of dementia in the aged population. The key feature of AD is the deposition of two different kinds of protein aggregates in the brain, and at the point of aggregate formation, treatment becomes difficult. A recent study focused on how to prevent the aggregation of one protein: the microtubule-associated protein Tau, which forms neurofibrillary tangles. Following up on research indicating that polyphenolic compounds can serve as neuroprotective agents, researchers analyzed the ability of the polyphenol Baicalein to inhibit the aggregation of Tau. In vitro, Baicalein blocked Tau aggregation and paired helical filament dissolution via an oligomer capture and dissociation mechanism. It also dissolved preformed mature fibrils of Tau, creating Tau oligomers, with no effect on the viability of neuronal cells..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Bakers: also referred to as dough mixer, micer, or pastry chef.

What they do:
Mix and bake ingredients to produce breads, rolls, cookies, cakes, pies, pastries, or other baked goods.

On the job, you would:
Check products for quality, and identify damaged or expired goods.
Set oven temperatures, and place items into hot ovens for baking.
Combine measured ingredients in bowls of mixing, blending, or cooking machinery.

This is an information sheet on the species, Balaeniceps rex, provided by the University of Michigan Museum of Zoology.

This video lecture presents the basic definitions of assets, liabilities and equity with simple examples. It also explains the concept of accounting equation with examples.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The transcription factor Nrf2 plays paradoxical roles in cancer biology. Transient Nrf2 activation can protect against cancer development, but permanent Nrf2 activation promotes progression and treatment resistance. Persistent activation can be triggered by Keap1-inactivating mutations that cause Nrf2 nuclear accumulation and/or by mutations in the ETGE and DLG motifs of Nrf2, which are important regions for Nrf2–Keap1 interaction. Epigenetic silencing of Keap1 and disruption of the Nrf2–Keap1 interaction by other proteins can also aberrantly activate Nrf2. Given the detrimental effects of excessive activation, pharmacologically balancing Nrf2 activity is a promising avenue for cancer treatment. Numerous Nrf2 activators have been discovered or developed, such as the synthetic compound oltipraz (OPZ) and the plant-derived compound curcumin (CUR). In general, Nrf2 activators can promote the functions of antioxidants, phase II detoxification factors, and transducers..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This collection makes available examples of a brilliant style of brass band music that flourished in the 1850s in the United States and remained popular through the nineteenth century. Bands of this kind served in the armies of both the North and the South during the Civil War. The collection includes both printed and manuscript music (mostly in the form of "part books" for individual instruments) and features over 700 musical compositions, as well as 8 full-score modern editions and 19 recorded examples of brass band music in performance.

There are many reasons to keep your money in a bank or credit union. The October 2020 issue of Page One Economics®: Focus on Finance describes what banks, credit unions, and online banks are and outlines things to consider when choosing where to have an account and what type of account to have.