This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"It’s a feared moment for every scientist: the discovery that years of painstaking research has led to results that can't be repeated. Many think that poorly characterized antibodies have contributed to this reproducibility crisis more than any other laboratory tool. A new study published in Molecular Cell supports this hypothesis, at least in the context of chromatin immunoprecipitation. Although accurate ChIP interpretation depends on near-perfect antibody specificity, the report shows that many of these reagents are far less capable than their advertising suggests, which calls into question several widely accepted paradigms on genomic regulation. The study focused on histone post-translational modifications; specifically all three methylation states of lysine 4 on histone H3. Through ChIP experiments, H3K4 methylation has been strongly linked to transcriptional control..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Word Count: 6578

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Word Count: 6578

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, the CMB4e iText (like earlier editions) remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship of cell structure and function. Rather than trying to be a comprehensive reference book, CMB4e selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in external links to supplementary material. The Basic CMB3e version of the iText includes links to external web-sources as well as the author’s short, just-in-time YouTube VOPs (with edited, optional closed captions), all embedded in or near relevant text. Each video is identified with a descriptive title and video play and QR bar codes.

Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Interpret the metazoan phylogenetic treeDescribe the types of data that scientists use to construct and revise animal phylogenyList some of the relationships within the modern phylogenetic tree that have been discovered as a result of modern molecular data

By the end of this section, you will be able to:Identify and describe the properties of lifeDescribe the levels of organization among living thingsRecognize and interpret a phylogenetic treeList examples of different sub disciplines in biology

By the end of this section, you will be able to:Identify and describe the properties of lifeDescribe the levels of organization among living thingsRecognize and interpret a phylogenetic treeList examples of different sub disciplines in biology

This course teaches the design of contemporary information systems for biological and medical data. Examples are chosen from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (e.g. C, C++, Java, Lisp, Perl, Python). A major term project is required of all students. This subject is open to motivated seniors having a strong interest in biomedical engineering and information system design with the ability to carry out a significant independent project.
This course was offered as part of the Singapore-MIT Alliance (SMA) program as course number SMA 5304.

This is a hands-on activity to assess the students understanding of peptide and disulfide bonds formed during protein synthesis. Students demonstrate the process of dehydration synthesis by combining amino acids through peptide bonds creating molecules of water, and one protein amino acid strand. It can also be used to assess students understanding of the process of translation.

CK-12’s Life Science delivers a full course of study in the life sciences for the middle school student, relating an understanding of the history, disciplines, tools, and modern techniques of science to the exploration of cell biology, molecular biology, genetics, evolution, prokaryotes, protists,fungi, plants, animals, invertebrates, vertebrates, human biology, and ecology. This digital textbook was reviewed for its alignment with California content standards.

There is growing body of evidence to support that students who directly experience authentic scientific research are more likely to continue onto advanced degrees and careers in Science, Technology, Engineering and Mathematics (STEM). In an effort to introduce more students to the benefits of scientific research we have drawn on an ongoing research project aimed at understanding how Corals Respond to the Environment (CRE) to develop an interdisciplinary laboratory course based on Authentic Research Experiences (ARE). A small cohort of undergraduate students enrolled in a semester-long course, entitled CREARE, perform biochemical experiments in the laboratory, analyze environmental data by R statistical software and prepared a report modeled after a research manuscript to present their work. The impact of CREARE on student learning gains and attitudes towards science is being measured, as is the impact of CREARE on participants' career choices and retention in STEM. This multidisciplinary research program addresses the impact of climate change on the health of a critically endangered coral species, ultimately leading to a better stewardship of this invaluable resource. Furthermore, CREARE offers a unique experience for students, one that may serve as a model for the development of more research-based courses, leading to improved retention in our STEM departments.

(Note: this resource was added to OER Commons as part of a batch upload of over 2,200 records. If you notice an issue with the quality of the metadata, please let us know by using the 'report' button and we will flag it for consideration.)

A grasp of the logic and practice of science is essential to understand the rest of the world around us. To that end, the CMB3e iText (like earlier editions) remains focused on experimental support for what we know about cell and molecular biology, and on showing students the relationship of cell structure and function. Rather than trying to be a comprehensive reference book, CMB3e selectively details investigative questions, methods and experiments that lead to our understanding of cell biology. This focus is nowhere more obvious than in the chapter learning objectives and in external links to supplementary material. In the freely available Basic CMB3e, the latter include the author’s short just-in-time YouTube VOPs, embedded near relevant text.

Like most introductory science textbooks, this one opens with a discussion of scientific method. A key feature is its focus on experimental support for what we know about cell and molecular biology. Understanding how science is practiced and how investigators think about experimental results is essential to understanding the relationship of cell structure and function…, not to mention our relationship to the natural world. This is a free Open Education Resource (OER), covered by a Creative Commons CCBY license (check out the Preface!). Every chapter begins with learning objectives and links to relevant recorded lectures. As used by the author, the iText engages students with embedded “just-in-time” learning tools. These include instructor’s annotations (comments) directing students to animations or text of interest, as well as links to writing assignments and quizzes. These interactive features aim to strengthen critical thinking and writing skills necessary to understand cell and molecular biology, not to mention science as a way of thinking in general. Please excuse the marketing terms, but you can choose between Bronze, Silver, or Gold versions, reflecting increasing potential for student interaction with the iText. Download your choice of the iText or the sample chapter at one of the links below.

Cellular respiration is the process by which our bodies convert glucose from food into energy in the form of ATP (adenosine triphosphate). Start by exploring the ATP molecule in 3D, then use molecular models to take a step-by-step tour of the chemical reactants and products in the complex biological processes of glycolysis, the Krebs cycle, the Electron Transport Chain, and ATP synthesis. Follow atoms as they rearrange and become parts of other molecules and witness the production of high-energy ATP molecules.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The skin is the interface between the human body and the environment, and the different features in distinct skin regions, such as different temperatures, humidity levels, gland densities, and pH values, create a variety of niches that can support a diverse skin microbiome. This microbiome includes bacteria, archaea, viruses, fungi, and even mites. A healthy skin microbiome helps maintain skin homeostasis, protects against pathogens, communicates with and trains the immune system, and affects wound healing. However, the skin microbiome can be influenced by many factors, including intrinsic factors like aging and extrinsic factors like cosmetic. Recent advances in molecular biology techniques and next-generation sequencing have drastically increased our understanding of the microorganisms that live on our skin, but the microbes are often still difficult to culture and study..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This genomics education lesson plan was formulated and tested on some year 6 students with the help of their teacher Michelle Pardini at the Hong Kong ICS School. Using the example of the ongoing citizen science Bahinia Genome project from Hong Kong it hopes to serve as a model to inspire and inform other national genome projects, and aid the development of crucial genomic literacy and skills across the globe. Inspiring and training a new generation of scientists to use these tools to tackle the biggest threats to mankind: climate change, disease, and food security. It is released under a CC-BY SA 4.0 license, and utilised the following slide deck and final quiz. Promoting open science, all of the data and resources produced from the project is immediately put into the public domain. Please feel free to utilise, adapt and build upon any of these as you wish. The open licence makes these open education resources usable just with attribution and posting of modified resources under a similar manner. Contact BauhiniaGenome if you have any questions or feedback.Bauhinia Genome overviewFor a slidedeck for the lesson plan laid out here you can use the set in slideshare here.