The COVID-19 Data Portal was launched in April 2020 to bring together relevant datasets for sharing and analysis in an effort to accelerate coronavirus research. This course provides a short overview of what the COVID-19 Data Portal is, how to access it and how to submit data.

By the end of the course you will be able to:
Explain the purpose of the COVID-19 Data Portal
Describe what data is accessible through the COVID-19 Data Portal
Know where to submit COVID-related data

During Fall 2021, all MIT students and the general public are welcome to join Professors Richard Young and Facundo Batista as they discuss the science of the COVID-19 pandemic. The livestream of the lectures is available to the public, but only registered students are able to ask questions during the Q&A.
Lectures will be given by leading experts on the fundamentals of coronavirus and host cell biology, immunology, epidemiology, clinical disease, and vaccine and therapeutic development. Guest faculty include Amy Barczak, Dan Barouch, Arup Chakraborty, Victoria Clark, Shane Crotty, Anthony Fauci, Britt Glaunsinger, Salim Karim, Shiv Pillai, Rochelle Walensky, Bruce Walker, Laura Walker, and Andrew Ward.

During Fall 2020, all MIT students and the general public were welcomed to join Professors Richard Young and Facundo Batista as they discussed the science of the pandemic during this new class. The livestream of the lectures was available to the public, but only registered students were able to ask questions during the Q&A. 
Special guest speakers included: Drs. Anthony Fauci, David Baltimore, James Bradner, Victoria Clark, Kizzmekia Corbett, Britt Glaunsinger, Akiko Iwasaki, Eric Lander, Michael Mina, Michel Nussenzweig, Shiv Pillai, Arlene Sharpe, Skip Virgin, and Bruce Walker.
NOTE: This class ran from September 1, 2020 through December 8, 2020.

CREATES is a set of 6 steps that help learners read and critically analyze scientific papers. The CREATES method, pioneered by Dr. Sally Hoskins, has a demonstrated positive impact on undergraduate students' self-confidence in scientific reading, as well as in their general perceptions of and beliefs about science and scientific thinking (Hoskins, et. al, 2017).

The new CREATES site, created in collaboration with Jordan Moberg Parker, UCLA's Director of Undergraduate Laboratory Curriculum and Assessment in Microbiology, Immunology, and Molecular Genetics, uses interactive media, step-by-step directions, and detailed annotation of authentic examples to guide students through the process.

Esse material didático é resultado das experiências do projeto de atuação na linha ambiente e sociedade do Programa de Pós-Graduação em Rede Nacional para o Ensino das Ciências Ambientais (PROFCIAMB), pela Universidade Federal do Amazonas (UFAM), tendo como base a dissertação “Abelhas nativas e educação ambiental: uma sequência didática interdisciplinar na formação do discente em agropecuária” que foi orientado pelo Prof. Dr. Neliton Marques da Silva.
Ele apresenta as sequências didáticas (SD’s) aplicadas junto a turma do 1º Ano do Curso Técnico de Nível Médio em Agropecuária na Forma Integrada, ofertados pelo IFAM campus Coari, com o objetivo de servir como um norteador para utilização das abelhas nativas sem ferrão como ferramenta educacional, especialmente na disciplina de ciências.

The University of California, Irvine Extension, supported by generous grants from the William and Flora Hewlett Foundation and The Boeing Company, is developing online courses to prepare science and mathematics teachers for the California Subject Examinations for Teachers (CSET).

UC Irvine Extension's online test-preparation courses correspond with the 10 CSET science subtests and three CSET mathematics subtests.

Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students (2021) is an undergraduate medical-level resource for foundational knowledge across the disciplines of genetics, cell biology and biochemistry. This USMLE-aligned text is designed for a first-year undergraduate medical course that is delivered typically before students start to explore systems physiology and pathophysiology. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. The text assumes that the students will have completed medical school prerequisites (including the MCAT) in which they will have been introduced to the most fundamental concepts of biology and chemistry that are essential to understand the content presented here. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.

The 276-page text was created specifically for use by pre-clinical students at Virginia Tech Carilion School of Medicine and was based on faculty experience and peer review to guide development and hone important topics.

Available Formats
978-1-949373-42-4 (PDF)
978-1-949373-43-1 (ePub) [coming soon]
978-1-949373-41-7 (Pressbooks) https://pressbooks.lib.vt.edu/cellbio
Also available via LibreTexts: https://med.libretexts.org/@go/page/37584

How to Adopt this Book
Instructors reviewing, adopting, or adapting parts or the whole of the text are requested to register their interest at: https://bit.ly/interest-preclinical.

Instructors and subject matter experts interested in and sharing their original course materials relevant to pre-clinical education are requested to join the instructor portal at https://www.oercommons.org/groups/pre-clinical-resources/10133.

Features of this Book
1. Detailed learning objectives are provided at the beginning of each subsection
2. High resolution, color contrasting figures illustrate concepts, relationships, and processes throughout
3. Summary tables display detailed information
4. End of chapter lists provide additional sources of information
5. Accessibility features including structured heads and alternative-text provide access for readers accessing the work via a screen-reader

Table of Contents
1. Biochemistry basics
2. Basic laboratory measurements
3. Fed and fasted state
4. Fuel for now
5. Fuel for later
6. Lipoprotein metabolism and cholesterol synthesis
7. Pentose phosphate pathway (PPP), purine and pyrimidine metabolism
8. Amino acid metabolism and heritable disorders of degradation
9. Disorders of monosaccharide metabolism and other metabolic conditions
10. Genes, genomes, and DNA
11. Transcription and translation
12. Gene regulation and the cell cycle
13. Human genetics
14. Linkage studies, pedigrees, and population genetics
15. Cellular signaling
16. Plasma membrane
17. Cytoplasmic membranes
18. Cytoskeleton
19. Extracellular matrix

Suggested Citation
LeClair, Renée J., (2021). Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students, Blacksburg, VA: Virginia Tech Publishing. https://doi.org/10.21061/cellbio. Licensed with CC BY NC-SA 4.0.

About the Author
Renée J. LeClair is an Associate Professor in the Department of Basic Science Education at the Virginia Tech Carilion School of Medicine, where her role is to engage activities that support the departmental mission of developing an integrated medical experience using evidence-based delivery grounded in the science of learning. She received a Ph.D. at Rice University and completed a postdoctoral fellowship at the Maine Medical Center Research Institute in vascular biology. She became involved in medical education, curricular renovation, and implementation of innovative teaching methods during her first faculty appointment, at the University of New England, College of Osteopathic Medicine. In 2013, she moved to a new medical school, University of South Carolina, School of Medicine, Greenville. The opportunities afforded by joining a new program and serving as the Chair of the Curriculum committee provided a blank slate for creative curricular development and close involvement with the accreditation process. During her tenure she developed and directed a team-taught student-centered undergraduate medical course that integrated the scientific and clinical sciences to assess all six-core competencies of medical education.

Accessibility Note
The University Libraries at Virginia Tech and Virginia Tech Publishing are committed to making its publications accessible in accordance with the Americans with Disabilities Act of 1990. The HTML (Pressbooks) and ePub versions of this book utilize header structures and include alternative text which allow for machine-readability.

Please report any errors at https://bit.ly/feedback-preclinical

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.

Like most introductory science textbooks, this one opens with a discussion of scientific method. A key feature is its focus on experimental support for what we know about cell and molecular biology. Understanding how science is practiced and how investigators think about experimental results is essential to understanding the relationship of cell structure and function…, not to mention our relationship to the natural world. This is a free Open Education Resource (OER), covered by a Creative Commons CCBY license (check out the Preface!). Every chapter begins with learning objectives and links to relevant recorded lectures. As used by the author, the iText engages students with embedded “just-in-time” learning tools. These include instructor’s annotations (comments) directing students to animations or text of interest, as well as links to writing assignments and quizzes. These interactive features aim to strengthen critical thinking and writing skills necessary to understand cell and molecular biology, not to mention science as a way of thinking in general. Please excuse the marketing terms, but you can choose between Bronze, Silver, or Gold versions, reflecting increasing potential for student interaction with the iText. Download your choice of the iText or the sample chapter at one of the links below.

This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience.

In this unit, students look at the components of cells and their functions and discover the controversy behind stem cell research. The first lesson focuses on the difference between prokaryotic and eukaryotic cells. In the second lesson, students learn about the basics of cellular respiration. They also learn about the application of cellular respiration to engineering and bioremediation. The third lesson continues students' education on cells in the human body and how (and why) engineers are involved in the research of stem cell behavior.

This textbook was written for collegiate Cell and Molecular Biology courses and may be appropriate at both an introductory level and also as a resource for more advanced courses.

In this course we will explore how altered metabolism drives cancer progression. Students will learn (1) how to read, discuss, and critically evaluate scientific findings in the primary research literature, (2) how scientists experimentally approach fundamental issues in biology and medicine, (3) how recent findings have challenged the traditional “textbook” understanding of metabolism and given us new insight into cancer, and (4) how a local pharmaceutical company is developing therapeutics to target cancer metabolism in an effort to revolutionize cancer therapy.

This quick tour provides a brief introduction to the Cellular Microscopy Phenotype Ontology (CMPO). It covers the scientific principles that led to the creation of this ontology and how it can be used.

By the end of the course you will be able to:
Describe the role of CMPO
Search and browse the ontology and use it to annotate data

This course serves as an introduction to the structure and function of the nervous system. Emphasis is placed on the cellular properties of neurons and other excitable cells. Topics covered include the structure and biophysical properties of excitable cells, synaptic transmission, neurochemistry, neurodevelopment, and the integration of information in simple systems and the visual system.

This course includes:

Surveying the molecular and cellular mechanisms of neuronal communication.
Coversion channels in excitable membrane, synaptic transmission, and synaptic plasticity.
Correlation of the properties of ion channels and synaptic transmission with their physiological function such as learning and memory.
Discussion of the organizational principles for the formation of functional neural networks at synaptic and cellular levels.

This course reviews the processing and structure of cellular materials as they are created from polymers, metals, ceramics, glasses, and composites, develops models for the mechanical behavior of cellular solids, and shows how the unique properties of honeycombs and foams are exploited in applications such as lightweight structural panels, energy absorption devices and thermal insulation. The applications of cellular solids in medicine include increased fracture risk due to trabecular bone loss in patients with osteoporosis, the development of metal foam coatings for orthopaedic implants, and designing porous scaffolds for tissue engineering that mimic the extracellular matrix. Modelling of cellular materials applied to natural materials and biomimicking is explored. Students taking the graduate version of the class are required to complete additional assignments.

Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

Students first discover what they want from their education, then build a plan to get there. This content takes students through the steps to successfully navigate their journey in higher education. Topics include planning for success, choosing a career path, setting and attaining goals, understanding financial management, developing critical thinking skills, making healthy choices, using effective communication, managing time, developing learning strategies, developing meaningful relationships. Content is available in PDF and Open Document formats and is licensed CC BY. Learning Objectives also are provided. Full course offering available at https://www.cengage.com/c/opennow-college-success-1e-opennow-cengage