Short Description:
Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students, is an undergraduate medical-level resource for foundational knowledge across the disciplines of genetics, cell biology and biochemistry. This text is designed for a course in first year undergraduate medical course that is delivered typically before students start to explore systems physiology and pathophysiology. The text is meant to provide the essential information from these content areas in a concise format that would allow learner preparation to engage in an active classroom. Clinical correlates and additional application of content is intended to be provided in the classroom experience. The text assumes that the students will have completed medical school prerequisites (including the MCAT) in which they will have been introduced to the most fundamental concepts of biology and chemistry that are essential to understand the content presented here. This resource should be assistive to the learner later in medical school and for exam preparation given the material is presented in a succinct manner, with a focus on high-yield concepts.NewParaAdditional versions of this book are freely available at: https://doi.org/10.21061/cellbio and https://med.libretexts.org/@go/page/37584.NewParaInstructors reviewing, adopting, or adapting parts or the whole of the text are requested to register their interest at: https://bit.ly/interest-preclinical. Instructors and subject matter experts interested in sharing original supplemental materials are invited to join https://www.oercommons.org/groups/pre-clinical-resources/10133.

Word Count: 63120

ISBN: 978-1-957213-05-7

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.

In this unit, students look at the components of cells and their functions and discover the controversy behind stem cell research. The first lesson focuses on the difference between prokaryotic and eukaryotic cells. In the second lesson, students learn about the basics of cellular respiration. They also learn about the application of cellular respiration to engineering and bioremediation. The third lesson continues students' education on cells in the human body and how (and why) engineers are involved in the research of stem cell behavior.

Short Description:
This book describes the simplified architecture of an IoT network from the core functional perspective and then presents step-by-step procedures to establish a connection between the IoT device and platform. It practically shows how to connect a cellular IoT module to the Microsoft Azure IoT Hub using the LTE-M technology.

Word Count: 11073

ISBN: 978-1-990132-03-2

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

In this course we will explore how altered metabolism drives cancer progression. Students will learn (1) how to read, discuss, and critically evaluate scientific findings in the primary research literature, (2) how scientists experimentally approach fundamental issues in biology and medicine, (3) how recent findings have challenged the traditional “textbook” understanding of metabolism and given us new insight into cancer, and (4) how a local pharmaceutical company is developing therapeutics to target cancer metabolism in an effort to revolutionize cancer therapy.

This quick tour provides a brief introduction to the Cellular Microscopy Phenotype Ontology (CMPO). It covers the scientific principles that led to the creation of this ontology and how it can be used.

By the end of the course you will be able to:
Describe the role of CMPO
Search and browse the ontology and use it to annotate data

This course includes:

Surveying the molecular and cellular mechanisms of neuronal communication.
Coversion channels in excitable membrane, synaptic transmission, and synaptic plasticity.
Correlation of the properties of ion channels and synaptic transmission with their physiological function such as learning and memory.
Discussion of the organizational principles for the formation of functional neural networks at synaptic and cellular levels.

This course reviews the processing and structure of cellular materials as they are created from polymers, metals, ceramics, glasses, and composites, develops models for the mechanical behavior of cellular solids, and shows how the unique properties of honeycombs and foams are exploited in applications such as lightweight structural panels, energy absorption devices and thermal insulation. The applications of cellular solids in medicine include increased fracture risk due to trabecular bone loss in patients with osteoporosis, the development of metal foam coatings for orthopaedic implants, and designing porous scaffolds for tissue engineering that mimic the extracellular matrix. Modelling of cellular materials applied to natural materials and biomimicking is explored. Students taking the graduate version of the class are required to complete additional assignments.

Life as an emergent property of networks of chemical reactions involving proteins and nucleic acids. Mathematical theories of metabolism, gene regulation, signal transduction, chemotaxis, excitability, motility, mitosis, development, and immunity. Applications to directed molecular evolution, DNA computing, and metabolic and genetic engineering.

This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.
Lecturers
Frederick W. Alt, Marcus Altfeld, Paul Anderson, Jon C. Aster, Hugh Auchincloss, Steven P. Balk, Samuel M. Behar, Richard S. Blumberg, Francisco Bonilla, Bobby Cherayil, Benjamin Davis, David Hafler, Nir Harcohen, Bruce Horwitz, David M. Lee, Andrew Lichtman, Diane Mathis, Richard Mitchell, Hidde Ploegh, Emmett Schmidt, Arlene Sharpe, Megan Sykes, Shannon Turley, Dale T. Umetsu, Ulrich von Andrian, Bruce Walker, Kai Wucherpfennig, Ramnik Xavier, Sarah Henrickson

Students first discover what they want from their education, then build a plan to get there. This content takes students through the steps to successfully navigate their journey in higher education. Topics include planning for success, choosing a career path, setting and attaining goals, understanding financial management, developing critical thinking skills, making healthy choices, using effective communication, managing time, developing learning strategies, developing meaningful relationships. Content is available in PDF and Open Document formats and is licensed CC BY. Learning Objectives also are provided. Full course offering available at https://www.cengage.com/c/opennow-college-success-1e-opennow-cengage

Students first discover what they want from their education, then build a plan to get there. This content takes students through the steps to successfully navigate their journey in higher education. Topics include planning for success, choosing a career path, setting and attaining goals, understanding financial management, developing critical thinking skills, making healthy choices, using effective communication, managing time, developing learning strategies, developing meaningful relationships. Content is available in PDF and Open Document formats and is licensed CC BY. Learning Objectives also are provided. Full course offering available at https://www.cengage.com/c/opennow-college-success-1e-opennow-cengage

Students first discover what they want from their education, then build a plan to get there. This content takes students through the steps to successfully navigate their journey in higher education. Topics include planning for success, choosing a career path, setting and attaining goals, understanding financial management, developing critical thinking skills, making healthy choices, using effective communication, managing time, developing learning strategies, developing meaningful relationships. Content is available in PDF and Open Document formats and is licensed CC BY. Learning Objectives also are provided.

This activity engages learners in exploring the impact of climate change on arctic sea ice in the Bering Sea. They graph and analyze sea ice extent data, conduct a lab on thermal expansion of water, and then observe how a scientist collects long-term data on a bird population.

This quick tour provides a brief introduction to ChEBI, the EBI's Chemical Entities of Biological Interest database, which focuses on 'small' chemical compounds.

By the end of the course you will be able to:
explain what the ChEBI Database is and how you can use it to access chemical compounds of interest
demonstrate where to find out more about ChEBI

Chemical Entities of Biological Interest (ChEBI) is a user-friendly online chemical dictionary that focuses on the nomenclature, structure, and biological properties of 'small' molecules that may be encountered by anyone working in molecular biology. This course will show you what kind of information is available in ChEBI and how to access and query the database.

By the end of the course you will be able to:
Evaluate what ChEBI is and how it can be useful in your day-to-day research
Know what data are stored and how ChEBI classifies molecules (understanding ChEBI ontology)
Be able to carry out different types of search

This quick tour provides a brief introduction to ChEMBL, the EMBL-EBI's chemogenomics resource.

By the end of the course you will be able to:
Describe what ChEMBL is and how it can help you to understand the interactions between drugs or drug-like molecules and their targets
Recall where to find out more about ChEMBL

How would you like to travel to new places while collaborating on a geospatial data challenge with students from around the world? In this class, students collaborate on a global-scale geospatial analysis problem with a focus on data analytics and professional practice in Geographic Information Systems. Penn State MGIS students collaborate with graduate students from ITC - University of Twente in Enschede, Netherlands to develop solutions to analyze spatio-temporal patterns in refugee migration data. Students have the opportunity to present their work and develop new connections with EU geospatial professionals via site visits to European national mapping agencies. Students work in teams to use geospatial analytics to arrive at a solution to visualize patterns over space and time.

Welcome to Charting Your Course: A Roadmap to Thriving in the Field of Health! Whether you are in your first semester, nearing graduation, or long past graduation, this career guide is designed to lead you through the career development process: from building self-awareness, to conducting career research, undertaking a job search, to succeeding on the job. Charting Your Course includes relevant, up-to-date information, interactive and self-reflection-based exercises, as well as online resources to help support you to become more comfortable, flexible, and adept at managing your career.

Word Count: 53340

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)