Mutation Detective is a text-based game using the platform Twine. In this …
Mutation Detective is a text-based game using the platform Twine. In this game, students choose “cases” of genetic mutations. They are first given the original and mutated amino acid sequences, then can go further to the original and mutated RNA sequences. The goal is to guess what kind of mutation has occured and provide evidence for it. There are also checkpoints throughout for them to take notes in their science notebook.
In terms of life science content, evolution is essentially where genetics meets …
In terms of life science content, evolution is essentially where genetics meets ecology. In this introduction to evolution, students will take on the role of both research biologists and predators to simulate how environmental conditions affect and change a population of model frogs and traits. Students will encounter the impacts of mutations and changes to the environment affecting the survival as well. This lesson results from a collaboration between the Alabama State Department of Education and ASTA.
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"St. Louis University researchers have discovered some of the molecular processes that lead to decline in patients with progeria. Their work also helps explain why certain drugs seemingly rejuvenate progeria cells, which could hint at more potent therapies against progeria. Hutchinson–Gilford progeria syndrome is a rare genetic disease that causes premature aging. Rapid aging of different tissues causes death by teenage years, normally due to cardiovascular complications. Currently, therapies for this devastating disease provide patients minimal benefit. The origin of progeria is a mutation in the lamin A gene—responsible for fabricating structural proteins that help keep the cell nucleus sturdy and the genome intact. The mutated lamin A protein “progerin” destabilizes the cell nucleus, causes DNA damage, and ultimately leads to the aging effects found in patients with progeria. Now, the researchers have delved deeper to understand how progerin wreaks damage at the molecular level..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
On this site, through a variety of activities, you can learn about …
On this site, through a variety of activities, you can learn about anthropology, archaeology, astronomy, biodiversity, the brain, climate change, the Earth, Einstein, expeditions, genetics, marine biology, paleontology, water, and zoology.
This Ology website for kids focuses on Genetics. It includes activities, things …
This Ology website for kids focuses on Genetics. It includes activities, things to make, quizzes, interviews with working scientists, and more to help kids learn about Genetics.
A network of online databases provides essential information for researchers in molecular …
A network of online databases provides essential information for researchers in molecular biology. These databases give researchers quick access to current information on genes, proteins, model organisms and publications. This module introduces students to the basic structure of databases and the process for submitting information to databases. Students use several of these databases to collect information on a yeast gene of their choice. This module is part on a semester-long introductory lab course, Investigations in Molecular Biology, at Boston College
A video that makes the unspoken assumptions that we use in pedigree …
A video that makes the unspoken assumptions that we use in pedigree analysis explicit through a skit of two students solving a challenging pedigree question over videoconference. The students discuss certain pedigree assumptions which are often not mentioned in other pedigree teaching materials, even though they can be important to solving complex problems. The students recognize that not all assumptions are always applicable and sometimes we need to reconsider which assumptions to use.Includes two videos: a version without subtitles and a version with subtitles
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Genetic sequencing is faster and cheaper than ever. But are the latest techniques more reliable than traditional ones? Scientists at the Dasman Diabetes Institute and Kuwait University are investigating that question for one of the trickiest genetic diseases to diagnose: autosomal dominant polycystic kidney disease. ADPKD is an inherited disease in which clusters of fluid-filled cysts accumulate in both kidneys, leading to increased kidney volume, impaired kidney functions, and, ultimately, kidney failure. In fact, ADPKD is the fourth leading cause of kidney failure, affecting one in every 800 to 1000 people worldwide. People with ADPKD may also develop cysts in the liver and other complications. The cause: mutations in genes PKD1 and PKD2. Genetic diagnosis allows doctors to detect the disease before symptoms even arise. The gold standard for doing so is Sanger sequencing. This technique sequences one DNA fragment at a time to detect mutations in the genome..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
The advent of rapid methods for sequencing DNA has resulted in major …
The advent of rapid methods for sequencing DNA has resulted in major advances in our understanding of the Evolution and distribution of a wide variety of marine organisms. Join Scripps researcher Ron Burton as he describes the surprising array of applications for these techniques in marine science. (56 minutes)
How will researchers harness the genetic potential of marine organisms? Join Dr. …
How will researchers harness the genetic potential of marine organisms? Join Dr. Terry Gaasterland as she describes how scientists at the new Scripps Genome Center are pioneering research in marine genomes. (54 minutes)
Join Mark Hildebrand on a journey from the open waters of the …
Join Mark Hildebrand on a journey from the open waters of the world's oceans to sophisticated genetics labs and ultimately to the incredible world of nanotechnology and marvel at ground-breaking applications he and his colleagues are finding for diatoms, one of the smallest and most important marine organisms. (49 minutes)
In this activity, students are assigned different alleles of the gene for …
In this activity, students are assigned different alleles of the gene for phenylalanine hydroxylase to research using OMIM (Online Mendelian Inheritance in Man). They are then asked to both explain and illustrate how this mutation may cause the disease phenylketonuria (PKU).
This text has been compiled to provide an overview of how plant …
This text has been compiled to provide an overview of how plant breeders develop cultivars of plant species. The methods that breeders use depend directly on the type of cultivar used to produce a commercial crop. The four most common types of cultivars are (a) clonal cultivars (b) synthetic cultivars (c) pure-line cultivars and (d) hybrid cultivars. These types of cultivars will be discussed throughout the book, alongside review questions for self-study.
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