Artemision Zeus or Poseidon, c. 460 B.C.E., bronze, 2.09 m high, Early …
Artemision Zeus or Poseidon, c. 460 B.C.E., bronze, 2.09 m high, Early Classical (Severe Style), recovered from a shipwreck off Cape Artemision, Greece in 1928 (National Archaeological Museum, Athens). Speakers: Dr. Beth Harris and Dr. Steven Zucker. Created by Steven Zucker and Beth Harris.
Although the information on this page is based around the anatomy of …
Although the information on this page is based around the anatomy of the canine hindlimb, it is essentially the anatomy of the arteries in domestic species. Any major differences will be discussed on their respective pages
This resource is a video abstract of a research paper created by …
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies, and 40% of cases are related to mutation of the oncogene KRAS. However, no KRAS-targeting drugs are currently available for cancer treatment, and patients with KRAS mutations are insensitive to anti-EGFR therapy, which is often used for CRC. To improve treatment options, a new study tested the combined effects of the drugs artesunate and WNT974 on KRAS-mutant CRC. In vitro, the combination synergistically reduced CRC growth and decreased KRAS protein levels and activity, while inducing KRAS degradation via the ubiquitin–proteasome pathway, thereby reducing the oncogene’s influence. Specifically, the induced KRAS degradation was mediated by upregulation of ANAPC2, as well as upregulation of β-TrCP and GSK-3β. In addition, the combination treatment suppressed the PI3K/Akt/mTOR pathway, which is downstream of KRAS and supports tumor growth..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
After researching the characteristics of arthropods, students observe arthropods in the field, …
After researching the characteristics of arthropods, students observe arthropods in the field, analyze their data, and learn how to develop their own arthropod collection. The unit is designed to be completed in eight or more sessions. The comprehensive curriculum materials contain information for teachers, including activity tips and an overview of the characteristics that define arthropods.
This unit, in which students prepare to observe arthropods in their field …
This unit, in which students prepare to observe arthropods in their field site's different microhabitats, helps set the stage for a discussion on the ramifications of habitat loss. It's designed to be completed in four or more sessions and has comprehensive curriculum materials for teachers, including activity tips and an overview of the microhabitats in a temperate forest. The unit is designed to answer the following two target questions. What microhabitats exist at our site? Do different arthropods occur in different microhabitats?
The course examines the earliest emergence of stories about King Arthur and …
The course examines the earliest emergence of stories about King Arthur and the Knights of the Round Table in the context of the first wave of British Imperialism and the expanded powers of the Catholic Church during the twelfth and thirteenth centuries. The morphology of Arthurian romance will be set off against original historical documents and chronicle sources for the English conquests in Brittany, Wales, Scotland, and Ireland to understand the ways in which these new attitudes towards Empire were being mythologized. Authors will include Bede, Geoffrey of Monmouth, Chrétien de Troyes, Marie de France, Gerald of Wales, together with some lesser known works like the Perilous Graveyard, the Knight with the Sword, and Perlesvaus, or the High History of the Holy Graal. Special attention will be paid to how the narrative material of the story gets transformed according to the particular religious and political agendas of each new author.
A deep dive into Article III of the Constitution, which establishes the …
A deep dive into Article III of the Constitution, which establishes the judicial branch of the government, including the Supreme Court. In this video, Kim discusses Article III with scholars Richard Garnett and Jeffrey Rosen.
A deep dive into Article II of the US Constitution, which establishes …
A deep dive into Article II of the US Constitution, which establishes the powers of the president. In this video, Kim discusses Article II with scholars Michael Gerhardt and Sai Prakash.
A deep dive into Article IV of the Constitution, which lays out …
A deep dive into Article IV of the Constitution, which lays out how federalism, the system of shared governance between states and the federal government, works in practice. In this video, Kim discusses Article IV with scholars Gabriel Chin and Erin Hawley.
A deep dive into Article I of the US Constitution, which describes …
A deep dive into Article I of the US Constitution, which describes the roles and powers of Congress. In this video, Kim discusses Article I with scholars Heather Gerken and Ilya Somin.
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