Instructional video on the formation of catenane after replication of circular bacterial chromosome.

Although textbooks describe this process and show illustrations, it is difficult to grasp without seeing a live demonstration.

Created for Biology 41 General Genetics at Tufts University.

For more than two decades J. Craig Venter and his research teams have been pioneers in genomic research. Regarded as one of the leading scientist of the 21st century, Venter discusses how he is applying tools and techniques developed to sequence the human genomes to discover new genes of microbes from around the world. (57 minutes)

Introduction to gel electrophoresis. How it's used to separate DNA fragments or other macromolecules.

This problem challenges students to design experiments using techniques measuring gene expression (reverse transcriptase PCR, microarrays, in situ hybridization).

Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

An integrated course stressing the principles of biology. Life processes are examined primarily at the molecular and cellular levels. Intended for students majoring in biology or for non-majors who wish to take advanced biology courses.

This fill-in-the-blank timeline is a planning tool for teachers to use when figuring out when to begin the steps associated with conducting a two-generation artificial selection experiment using Fast Plants. Teachers preparing for any selection experiment will find this timeline helpful, including those planning for the AP Biology Lab 1 of Big Idea 1: Evolution, Artificial Selection.

The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.

The aim of the course has always been a practical one. We want to give students practice in performing the commonest techniques in molecular biology and genetic engineering as well as providing a good basic understanding of how the techniques worked. Though you won’t be doing the wet lab part of the course this semester, you will get some experience via simulations and other “lab exercises” and you will get plenty of experience in planning and designing constructs to answer biological questions. Part of our aim is to prepare students for a career in genetic engineering and this hasn’t changed.

The goal of the Genetic Origins Program is to allow students to use their own DNA variations (polymorphisms) as a means to explore our shared genetic heritage and its implications for human health and society. Genetic Origins focuses on two types of DNA variations: an Alu insertion polymorphism on chromosome 16 (PV92) and single nucleotide polymorphisms (SNPs) in the control region of the mitochondrial (mt) chromosome. With two alleles and three genotypes, PV92 is a simple genetic system that illustrates Mendelian inheritance on a molecular level. PV92 data is readily analyzed using population statistics. The mt control region is one of the simplest regions of human DNA to sequence. With a high mutation rate, the mt control region is the "classical" system for studying human and primate evolution. The Genetic Origins site and linked Bioservers site have all the information needed for students to perform the Alu and mt DNA experiments and analyze the results - including online protocols, reagents, animations and videos explaining key concepts, and database tools.

With the emerging genetic testing companies such as “23 and Me” and “Ancestry”, it is becoming more popular and accessible for families to test their own genes rather than from a primary care provider. The purpose of this activity is to analyze multiple angles of genetic testing. Students will look at multiple areas of health including mental, emotional, and physical health and how it can impact their personal health and the health of loved ones.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Obesity and metabolic disorders are abnormally high in the Middle East. According to the World Health Organization, approximately 41% of all deaths in Kuwait are caused by cardiovascular disease. And after the US, Kuwait is the nation with the highest rate of obesity in the world. While overeating and an increasingly sedentary lifestyle are partially to blame, they’re not the only culprits. A new study from the Dasman Diabetes Institute in Kuwait suggests that genetic adaptations once key to survival for Kuwaiti ancestors predispose today’s population to debilitating disease. Traits like insulin resistance and hypertension spell trouble for modern, largely sedentary humans. But for the nomadic forbearers of today’s Kuwaiti population, they offered an advantage. An active metabolism and high blood pressure stimulate the sympathetic nervous system’s “fight-flight-or-freeze” response, favoring survival under the harsh desert climate of the Arabian Peninsula..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The aphid -- one of the most common crop pests in the world -- has a weakness that scientists have now learned to exploit. When attacked by predators, the bugs release a pheromone to tell fellow insects to scatter. Biologists have proposed spraying these alarm pheromones directly on crops to prevent pest damage, but synthesis is costly. With the advent of genetic engineering, though, the cheaper option is to modify crops to produce the deterrents themselves. In 2015, biologists at Rothamsted Research, an agricultural research station in the UK, reported the first engineering feat of this kind in wheat. To make wheat release insect pheromones, the group inserted a gene from the peppermint plant, which allows plants to produce the appropriate chemical. Then, they tested whether the altered plants’ volatile compounds were capable of repelling the pests..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Genetic mutations provide valuable tools for analyzing biochemical pathways in yeast. In this module, students use deletion mutants to analyze the steps in methionine biosynthesis in Saccharomyces cerevisiae. At the end of this module, students will be able to:understand and use the correct genetic nomenclature for genes, proteins and mutant strainsexplain how genetic screens are used to isolate mutant strains with particular phenotypesdistinguish various met deletion strains by their ability to grow on selective media containing different sulfur sources and by their appearnace on indicator mediapredict how mutations in various MET  genes will affect the intracellular concentrations of intermediates in the methionine biosynthesis This module is part of a semester-long introductory lab class, Investigations in Molecular Cell BIology, at Boston College.

In this video profile adapted from NOVA scienceNOW, learn about geneticist and rock musician Pardis Sabeti, whose innovative insights into natural selection demonstrated how beneficial mutations spread quickly through a population.

This science resource covers a variety of topics; however, the specific URL is on Genetics. It has significant explanations on the basic Principles of Genetics, Co-dominance, Incomplete dominance, and Sex-Linked traits. The units have precise and manageable explanations, and there are numerous links and additional resources to support instructors and students to advance learning. The access to videos and online simulations enhances particular areas, and the diverse assessments support mastery of skills.
This is a very purposeful resource on genetics; it is useful to make learning more effective either as an overall instructional method or as an individualized learning supplement.

This activity begins with sections that help students to understand basic principles of genetics, including (1) how genotype influences phenotype via the effects of genes on protein structure and function and (2) how genes are transmitted from parents to offspring through the processes of meiosis and fertilization. Then, a coin flip activity models the probabilistic nature of inheritance and Punnett square predictions; this helps students understand why the characteristics of children in many real families deviate from Punnett square predictions. Additional concepts covered include polygenic inheritance, incomplete dominance, and how a new mutation can result in a genetic condition that was not inherited. This activity helps students meet the Next Generation Science Standards.

this was a flipped classroom assignment for a Biology class. It has a few starter questions and a video to watch. The students will watch the video and take Cornell Style notes.