This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The transcription factor ATF5 plays a vital role in the formation of several cancers, including breast, lung, ovarian, pancreatic, rectal, and liver cancer. But ATF5’s function in esophageal cancer—one of the most common forms of cancer worldwide—remains unclear. To find out, researchers monitored the activity of ATF5 in esophageal cancer tissues. Much like in other cancers, ATF5 was upregulated in esophageal cancer tissues cultured in the lab, and ATF5 overexpression promoted the proliferation, migration, and invasiveness of esophageal cancer cells. Silencing ATF5, however, inhibited these abilities. In fact, in mice, silencing ATF5 hampered tumor growth. ATF5’s role as a lever that triggers tumor growth is believed to occur through an interaction with HIF1, a protein complex also known to promote the growth and spread of tumors. These findings suggest that the known anti-cancer effects of silencing ATF5 might also be powerful against esophageal cancer..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Entered according to Act of Congress in the year 1864 by M.E. Goodwin in the Clerk's Off. in the Dist. Court of the United States for the Southern Dist. of N.Y. Designed by R.D. Goodwin.|Title appears as it is written on the item.|Forms part of: American cartoon print filing series (Library of Congress)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The non-receptor tyrosine kinase Abelson (Abl) is a key player in oncogenesis, causing diseases including chronic myelogenous and acute lymphoblastic leukemia. Drugs targeting Abl kinase activity serve as paradigms of targeted therapy. Drosophila is an ideal model for studying Abl’s function because there is only a single fly Abl family member. In flies, Abl is essential for embryonic morphogenesis, playing diverse roles in embryonic and adult viability. To examine the role of the intrinsically disordered region (IDR) of Abl, researchers deleted the IDR in Drosophila. They found that Abl lacking the IDR was not able to rescue the roles of Abl in viability and embryonic morphogenesis. The IDR was also essential for cell shape changes and cytoskeletal regulation during embryonic morphogenesis and, surprisingly, for modulating protein stability..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Osteochondritis dissecans, or OCD, is a bone disease that wears away joints and the cartilage that covers them. It occurs most often in children and adolescents. While OCD has been documented and studied for nearly 150 years, researchers still don’t know what causes it. Reporting in The American Journal of Sports Medicine, one group offers up new findings that point to at least one factor that surgeons should look out for. The team looked at radiographs of 61 knees of patients undergoing surgery for OCD. Those patients were just over 23 years old on average, and 77% of them were men. The researchers reviewed the radiographs for mechanical alignment, as previous studies have speculated that deformities due to malalignment contribute to OCD. What they found was that patients with OCD did in fact show signs of off-axis effects. Specifically, they observed that the location of OCD lesions correlated with the deviation of the mechanical axis of the leg..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

A satire on enforcement of the "gag-rule" in the House of Representatives, prohibiting discussion of the question of slavery. Growing antislavery sentiment in the North coincided with increased resentment by southern congressmen of such discussion as meddlesome and insulting to their constituencies. The print may relate to John Quincy Adams's opposition to passage of the resolution in 1838, or (more likely) to his continued frustration in attempting to force the slavery issue through presentation of northern constituents' petitions in 1839. In December 1839 a new "gag rule" was passed by the House forbidding debate, reading, printing of, or even reference to any petition on the subject of abolition. Here Adams cowers prostrate on a pile composed of petitions, a copy of the abolitionist newspaper the "Emancipator," and a resolution to recognize Haiti. He says "I cannot stand Thomson's [sic] frown." South Carolina representative Waddy Thompson, Jr., a Whig defender of slavery, glowers at him from behind a sack and two casks, saying "Sir the South loses caste whenever she suffers this subject to be discussed here; it must be indignantly frowned down." Two blacks crouch behind Thompson, one saying "de dem Bobolishn is down flat!" Weitenkampf cites an impression with an imprint naming Robinson as printer and publisher, this line being apparently trimmed from the Library's impression. The drawing style and handling of the figures strongly suggest that "Abolition Frowned Down" is by the same Robinson artist as the anonymous "Called to Account" and "Symptoms of a Duel" (nos. 1839-10 and -11).|Drawn by HD?|Entd . . . 1839 by H.R. Robinson . . . Southn. Dist. of N.Y.|Title appears as it is written on the item.|Weitenkampf, p. 59.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1839-12.

The abomasum is the fourth chamber in the ruminant. It functions similarly to the carnivore stomach as it is glandular and digests food chemically, rather than mechanically or by fermentation like the other 3 chambers of the ruminant stomach.

BCC Bioscience Image Library is a media file repository of images and video clips made freely available to the public, with special attention to the needs of educators and students in the biological sciences. The resources are licensed under Creative Commons 0. This means all content is free, with no restrictions on how the material may be used, reused, adapted or modified for any purposes, without restriction under copyright or database law.

This project was partially funded by a $20,000,000 grant awarded by the U.S. Department of Labor’s Employment and Training Administration, Grant # TC-26450-14-60-A-25. The product was created by the grantee and does not necessarily reflect the official position of the U.S. Department of Labor. The U.S. Department of Labor makes no guarantees, warranties, or assurances of any kind, express or implied, with respect to such information, including any information on linked sites and including, but not limited to, accuracy of the information or its completeness, timeliness, usefulness, adequacy, continued availability, or ownership.

If you have any questions contact professor Faye Reynolds at: bioimagesoer@gmail.com

This video segment adapted from First Light explains why the highest peak in the Pacific, Mauna Kea, is an ideal site for astronomical observations. Featured are new telescope technologies that allow astronomers to explore the universe in more depth.

A selection of Library of Congress primary sources exploring Abraham Lincoln and his national role. This set also includes a Teacher's Guide with historical context and teaching suggestions. Speeches, correspondence, campaign materials and a map documenting the free and slave states in 1856 chronicle Lincoln���s rise to national prominence

This art history video discussion examines Jackson Pollock's "One: Number 31", 1950, Oil and enamel paint on unprimed canvas, 1950 (MoMA).

This document uses headings to allow students to begin the search with either the codon or the amino acid.

Il s’agit d’un  fichier Excel (Outil de gestion du stock)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The Isthmus of Tehuantepec in Mexico is one of the windiest places on earth making it a hotspot for investment in wind energy. But that’s proving problematic. Because although wind-energy investments appear to be paving the way toward a sustainable future a new study reports that a lack of good governance is proving unsustainable for the large indigenous population that calls the Isthmus home. Mexico is among the many nations that have implemented policies supporting the Sustainable Development Goals established by the United Nations. a blueprint for achieving a sustainable future for our planet. But in the Isthmus of Tehuantepec, these efforts do not adequately include local indigenous communities. It’s a problem caused by a combination of corruption, poor accountability, and limited access to information about energy and the environment. Fortunately, paths for reversing these poor governance patterns do appear to exist..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Produto educacional destinado, principalmente a pescadores artesanais e comunidades ligadas a pesca artesanal, contendo informações sobre espécies relacionadas a acidentes que envolvem animais aquáticos e pescadores artesanais, o perigo de determinados procedimentos inadequados e procedimentos recomendados como medidas de primeiros socorros.

It's no secret that greenhouse gases warm the planet and that this has dire consequences for the environment whole islands swallowed up by rising seas, animal and plant species stressed by higher temperatures, and upsets in ecological interactions as populations move to cooler areas. However, carbon dioxide has another, less familiar environmental repercussion: making the Earth's oceans more acidic. Higher levels of carbon dioxide in the atmosphere mean that more carbon dioxide dissolves in the ocean. This dissolved carbon dioxide forms carbonic acid the same substance that helps give carbonated beverages their acidic kick. While this process isn't going to make the ocean fizzy anytime soon, it is introducing its own set of challenges for marine organisms like plankton and coral.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Actinobacteria are some of the most widely distributed bacteria in soils and are well known for their ability to degrade plant residues in pure culture in the laboratory. Yet, despite the importance of microbe-driven decomposition to carbon sequestration in terrestrial systems, their importance and specific activity across diverse environments in the field are unknown. Researchers recently evaluated the ecophysiological roles of Actinobacteria in rice straw residue decomposition in a series of field and microcosm experiments. They found that although Actinobacteria represented only 4.6% of the total bacterial abundance, they encoded 16% of the total carbohydrate-active enzymes (CAZymes) involved in the breakdown of carbohydrates. The researchers also found that Actinobacteria taxonomic and functional compositions were relatively stable during straw decomposition and that the importance of Actinobacteria in decomposition increased as soil fertility decreased..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This visual representation is away for parents to understand how UDL uses Action and Expression (the "How" of learning)

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Humans rely on microbial communities in both natural and applied settings. One such applied setting is wastewater treatment plants, which use microbial communities to remove pollutants. However, the stability of the taxonomic diversity in these settings is not well understood. To close this gap, researchers examined how the microbial community in activated sludge changed over time in a full-scale wastewater treatment plant. For the first 3 years of a 9-year series, the microbial community fluctuated around a stable average. Then a bleaching event, marked in red under the timeline, abruptly pushed the community to an alternative stable state, where the originally dominant Actinobacteriota were disproportionally depleted and replaced with Proteobacteria, but these taxonomic changes led to little change in either the metabolic profile of the community or system performance. In a fine-scale analysis of dynamics, the researchers identified cohorts that dominated at different periods..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Acute myeloid leukemia (AML) is a type of blood and bone marrow cancer with a low survival rate. One reason AML is so deadly is because it can evade the immune system, in part by downregulating proteins like MICA, which normally marks damaged or cancerous cells in the body for immune destruction. To improve treatment prospects, researchers recently searched for molecules that can restore MICA levels in AML cells. They found that the transcription factor KFL4 is involved in MICA expression. In addition, treating cultured AML cells with the KLF4-activating compound APTO253 successfully induced MICA expression, while inhibiting the expression of the cancer gene MYC. These changes made the AML cells more susceptible to being killed by immune cells. Although studies in animals and humans are still needed, these findings reveal that APTO253 can improve immune cells’ ability to detect and kill AML cells and suggest that targeting KFL4/MICA is a promising option for AML treatment..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.