Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.
By the end of this section, you will be able to:Explain how the binding of a ligand initiates signal transduction throughout a cellRecognize the role of phosphorylation in the transmission of intracellular signalsEvaluate the role of second messengers in signal transmission
As a young man, Takashi Hoshizaki was imprisoned on McNeil Island, Washington in 1944 for resisting the draft for World War II. His resistance was part of a broader legal battle for the civil rights of over 120,000 Japanese Americans, including Takashi's family, imprisoned in American concentration camps. This lesson includes a 7-minute introduction video, lesson plan notes, activities, vocabulary, and educator resources.
The purpose of this lesson is to create an engaging and low-cost science field trip/activity. An important aspect of this camp is to make the activities low cost to no cost so that rural schools that do not always have a lot of funding will still be able to invoke creativity through an engaging hands-on planetary/geological science project that takes them outside of the classroom. The students will be using google earth to create a hypothesis using geomorphological questions relating to planetary science and then testing their hypothesis outside local to the school. The activities will be able to be catered to any region and can also be built on based on available resources. The activities will encompass planetary science and geomorphological concepts with optional art additions. The activities will be geared towards grades 6th-8th but could easily be tailored to any grade level. Students will learn about planetary science and geomorphological key concepts and then apply them to their own region.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"For nearly 25 years, scientists have known of the neuroprotective properties associated with the protein called prosaposin. But exactly how prosaposin exerts these effects has been a matter of debate. Initial research using a neuroactive fragment of the protein, called TX14(A), identified two closely related receptors thought to mediate the actions of prosaposin. But this work was later challenged. Now, an international team of scientists has reported strong evidence that prosaposin does activate these receptors, which may help pave the way for a new class of neuroprotective drugs. Uncertainty over the status of prosaposin as an endogenous ligand for GPR37L1 and GPR37 has stemmed from the use of widely varying experimental conditions. The main inconsistency with past work was the use of cell lines derived from ovary, kidney or yeast to study the receptors. But this creates a physiological mismatch, as the receptors are almost exclusively expressed in the brain..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.