Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.
Bioethics is the study of the moral implications of new and emerging medical technologies and looks to answer questions such as selling organs, euthanasia and whether should we clone people. The series consists of a series of interviews by leading bioethics academics and is aimed at individuals looking to explore often difficult and confusing questions surrounding medical ethics. The series lays out the issue in a clear and precise way and looks to show all sides of the debate.
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- Health, Medicine and Nursing
- Life Science
- Material Type:
- University of Oxford
- Provider Set:
- University of Oxford Podcasts
- Jonathan Wolf|Julian Savulescu|Jeff McMahan|Peter Singer|Nick Bostrom|Onora O'Neill|Jonathan Wolf|Tim Lewens|Hanna Pickard|Molly Crocket|Patricia Churchland
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.
By the end of this section, you will be able to:Describe gel electrophoresisExplain molecular and reproductive cloningDescribe uses of biotechnology in medicine and agriculture
What does a technology look like that will change the world? Biotechnology has the power to alter all of our lives. The ability to manipulate genes in ways that benefit people is a powerful technology. In this lesson we will explore various benefits and applications of biotechnology. You will analyze different perspectives in the race to create biotechnology. From there you will decide how you feel about “playing with genes” and how that will impact your life.StandardsBio.B.3.2.4 Students will apply scientific thinking, processes, tools, and technologies in the study of genetics.
In The Botany of Desire, Michael Pollan explores risks inherent in one of the most widespread practices in modern agriculture. It's called monoculture, and it refers to cultivation of single or very similar varieties of a food crop on large acreages. In many cases, the variety is one that dominates the marketplace, like the Russet Burbank potato, whose shape makes it a favorite for cutting French fries, or one of the few apple varieties commonly seen in supermarkets. Monoculture may offer economic advantages, but Pollan argues that it brings serious environmental risks.
Students are introduced to the concept and steps of the engineering design process and taught how to apply it. Students first receive some background information about biomedical engineering (aka bioengineering). Then they learn about material selection and material properties by using a provided guide. In small groups, students learn of their design challenge (improve a cast for a broken arm), brainstorm solutions, are given materials and create prototypes. To finish, teams communicate their design solutions through class poster presentations.
In this video segment adapted from NOVA scienceNOW, scientists discuss a family of genes called FOXO that can significantly extend life span in worms—and in humans.
Cloning is an amazing technology that allows us to make exact copies of living organisms. From duplicating organs to designer babies, the possibilities are endless; however, there are numerous drawbacks to cloning creatures. In this lesson you will explore how cloning works and identify your core values and feelings on the concepts. And finally, you will produce a presentation that outlines the benefits and drawbacks of this technology.StandardsBIO.B.2.4Explain how genetic engineering has impacted the fields of medicine, forensics, and agriculture (e.g., selective breeding, gene splicing, cloning, genetically modified organisms, gene therapy).
This video from Nature offers a description of desirable traits in beef and dairy cattle.
In this video segment from Nature, learn about six different breeds of cattle.
In this animation produced by WGBH and Digizyme, Inc., see how molecules of DNA are separated using gel electrophoresis, and how this process enables scientists to compare the molecular variations of two or more DNA samples.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Researchers at the RIKEN Center for Sustainable Resource Science have developed a new genetic pathway that can be used to co-opt E. coli bacteria to produce maleate, one of the most important industrial chemicals in use today. A chief component in the coatings of substances like nylon and galvanized steel and an important stabilizing agent in pharmaceuticals, maleate is typically produced through harsh treatments of crude oil. But by using genetically engineered microorganisms to produce maleate, the researchers have developed a much more sustainable approach. Maleate is the end product of a complex chemical reaction. Bacteria don’t normally come equipped with machinery to power this reaction, so the researchers had to design a ground-up approach before they could start harvesting maleate. This required careful analysis of the intermediates needed for maleate synthesis and the identification of genes that could help E. coli make each of these molecules..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
In this video excerpt from NOVA, learn about the advantages, disadvantages, and ethical implications of preimplantation genetic diagnosis, or PGD, a technique used to screen embryos created through in vitro fertilization for diseases.
TED Studies, created in collaboration with Wiley, are curated video collections supplemented by rich educational materials for students, educators and self-guided learners. in What Makes Us Human?, TED speakers tackle humanitys oldest and deepest questions by playing with primates, excavating ancient remains, and DNA-mapping family trees. Explore how the next chapters of our own evolutionary story will be written thanks to new technologies that trace our origin.
The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors.
Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.
This video segment from the Secret of Life School Video: "On the Brink: Portraits of Modern Science" explores the genetics of breast cancer.
In Blazing a Genetic Trail, by the Howard Hughes Medical Institute, follow this three-step approach to treating genetic diseases.