Poster showing an American sailor among sailors from various countries. Title from item.
E. W. Clay's apocalyptic allegory has public opinion as a giant lever, tilting decisively in favor of the Whigs late in the presidential campaign of 1840. In a symbolic landscape masses of people climb onto the lever, which then nudges the great ball of "Loco Focoism" over a precipice. In the sky appears an eagle with a shield, arrows, and olive branches, holding a banner with the commentary: "With a log cabin and barrel of hard Cider for a fulcrum, public opinion for a "lever," with old Tip on the tip end the ball of Locofocoism will be rolled into oblivion and a gallant soldier raised to the white house. March 4th 1841." In the distance is a recently cleared field, the White House, and the Capitol. Van Buren and several others topple from the giant ball, on which also appears a strong box inscribed "Sub Treasury." A crowd of erstwhile supporters flee from the edge of the chasm, leaving behind "Treasury Notes." The print probably appeared in September 1840, since the Library's impression was deposited for copyright on September 24. Nancy Davison and Frank Weitenkampf both attribute the print to Edward W. Clay. This is supported by stylistic comparison with his other 1840 cartoons. The "W.C." signature appears to be a truncated form of his "EWC" monogram.|Entered . . . 1840 by J. Childs.|Published by John Childs, 90 Nassau Street New York.|Signed: W.C. inv. (Edward Williams Clay).|Title appears as it is written on the item.|Davison, no. 133.|Lorant, p. 158-159.|Weitenkampf, p. 66.|Forms part of: American cartoon print filing series (Library of Congress)|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1840-58.
The following is an alphabet reading and writing drill based on advertisements for fast food items, restaurants/chains, and multinational companies that should mostly be recognizable to students. Students are asked to work in pairs, read the ads and write them out on the accompanying sheet in Arabic and translate them to English.
In this art history video discussion Beth Harris and Steven Zucker examine Albrecht Altdorfer's "The Battle of Issus," 1529, oil on panel. Alte Pinokothek, Munich.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Certain gut microbes and their metabolites contribute to the progression of benign colorectal adenoma (CRA) into colorectal cancer (CRC), but the specific microbes, metabolites, and mechanisms involved are unclear. To learn more, researchers recently analyzed stool samples from patients with CRA or CRC and normal control (NC) subjects. The levels of certain stool metabolites significantly differed among the groups. For example, myristic acid and norvaline became more abundant with progression from health to CRC. The CRC-associated metabolites were largely branched- chain amino acids and aromatic amino acids and were involved in aminoacyl-tRNA biosynthesis pathways. A metabolite “signature” distinguished CRC samples from NC samples and CRC samples from CRA samples and the relationships among CRC-related metabolites and gut bacteria differed in the different sample types..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Autophagy is an important cellular recycling process that degrades misfolded proteins and damaged organelles. In typical (“canonical”) autophagy, membranes derived from the endoplasmic reticulum surround damaged materials that need to be degraded, and the proteins Atg5 and Atg7 help form specialized digestion compartments (autophagosomes), but another type of autophagy, called alternative autophagy, was recently discovered. In alternative autophagy, the membranes that envelop the damaged materials are derived from the trans-Golgi membrane, and Atg5 and Atg7 do not participate in autophagosome formation. Alternative autophagy seems to be activated primarily under conditions of cell stress, and it plays roles in many diseases, such as heart disease, neurodegenerative disease, cancer, inflammatory bowel disease, and bacterial infection..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"The gut microbiome interacts intimately with its human host, both in health and in disease. A recent study examined how different states of the gut microbiome might be linked to varying degrees of disease in rats. Researchers exposed rats to different concentrations of dextran sodium sulfate (DSS), a polysaccharide known to induce human-like colitis. The effects on the intestinal microbiome over time were tracked by gene profiling. The results provide some of the first experimental evidence of “alternative states” in the rat intestinal ecosystem. These are distinct microbial profiles related to markers of disease. Importantly, these alternative states were found to be tied to both the host and microbiome, rather than one or the other. That led to a conceptual model of how host inflammatory status and microbiome status interact and how the whole ecosystem may slip into and out of different states of disease..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Since its appearance in late 2019, COVID-19 has caused well over one million deaths worldwide. Large-scale testing and contact tracing remain critical for controlling viral spread. Complying with the US CDC and WHO protocols for sample collection requires a ready supply of inexpensive swabs and collection reagents. Unfortunately, CDC-approved clinical-grade sampling supplies are expensive, and additionally, current methods prevent further analysis of the microbiome due to the presence of antibiotics in viral transport media. Researchers sought out new testing supplies in a recent study comparing five consumer-grade swabs and one clinical-grade swab. They found that using 95% ethanol instead of viral transfer media reduced RNase activity, preserving samples for microbiome analysis, and extracting directly from the swab head instead of the surrounding liquid resulted in 2-4x higher RNA recovery than the clinical standard..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"When patients undergo general anesthesia, there’s a shift in the distribution of ventilation and perfusion throughout the lung, with more areas of the lung getting too much air, relative to the amount of blood flow, and others getting too little. This type of scatter is traditionally described by Riley’s three-compartment model, in which high-ratio lung regions getting less blood flow produce increases in the alveolar deadspace. But new work published in the journal Anesthesiology shows that this model fails to account for different blood solubilities of various anesthetics -- and shows how multicompartment models better predict what is happening in the lungs. The researchers extended an earlier study in anesthetized patients that found that partial pressure measurements of inhaled anesthetic in the lungs did not match those made for carbon dioxide -- and were inconsistent with the three-compartment theory..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"Glioma is the most common and lethal form of brain cancer. Among patients with the highest grade of glioma, fewer than 6% survive up to 5 years after diagnosis. Interestingly, glioma is extremely rare in one large population of patients patients with Alzheimer’s disease. That suggests that an anti-glioma molecule could play a critical role in the development of Alzheimer’s. In a recent study, researchers assessed one possible candidate: presenilin-1. Presenilin-1 is a protein that assists the formation of amyloid beta, the main component of the hallmark plaques found in the brains of patients with Alzheimer’s. Experiments showed that high presenilin-1 levels in glioma tissue from patients correlated with low tumor proliferation. Closer examination revealed that presenilin-1 kept cancer from spreading by preventing tumor cells from replicating their DNA. This mechanism could explain the poor prognosis of glioma patients with low levels of presenilin-1..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:
"There may be a silver lining for those at high risk for Alzheimer’s: as the chance of getting the disease goes up, certain treatments may become more effective. The risk of developing Alzheimer’s largely relies on a gene called APOE, with different variants conferring more or less risk. Usually, having a high-risk allele is bad news, but a group of researchers from New York University has reported that carrying the high-risk allele could actually boost responsiveness to immunotherapy, a promising new treatment option. The APOE gene helps determine how much beta-amyloid accumulates in the brain. Beta-amyloid starts as small misfolded bits of protein that clump together to form the plaques that are the hallmark of Alzheimer’s. As the plaques appear, the brain deteriorates, particularly in regions associated with memory. One way to potentially halt this process is to use antibodies that recognize beta-amyloid. The antibodies bind to the protein and signal to the immune system to clear it out..."
The rest of the transcript, along with a link to the research itself, is available on the resource itself.
The large, bold woodcut image of a supplicant male slave in chains appears on the 1837 broadside publication of John Greenleaf Whittier's antislavery poem, "Our Countrymen in Chains." The design was originally adopted as the seal of the Society for the Abolition of Slavery in England in the 1780s, and appeared on several medallions for the society made by Josiah Wedgwood as early as 1787. Here, in addition to Whittier's poem, the appeal to conscience against slavery continues with two further quotes. The first is the scriptural warning, "He that stealeth a man and selleth him, or if he be found in his hand, he shall surely be put to death. "Exod[us] XXI, 16." Next the claim, "England has 800,000 Slaves, and she has made them free. America has 2,250,000! and she holds them fast!!!!" The broadside is advertised at "Price Two Cents Single; or $1.00 per hundred.|N.Y. sold at the Anti-Slavery Office, 144 Nassau St. 1837.|Title appears as it is written on the item.|Wedgwood Portraits and the American Revolution, p. 116-117.|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1837-16.
Students learn the stories of two ambitious and courageous women artists in European history -- Luisa Roldan (also known as La Roldana) and Elisabeth Louise Vigee Le Brun -- and examine works by both. Students then research and write a short report on a female artist working today.
An allegorical illustration on the cover of a patriotic song, dedicated to the "National Guards of Philadelphia." A pronouncedly decollete Columbia or Liberty figure sits astride a bald eagle which flies over the globe. The eagle clutches lightning bolts and an olive branch in its talons, while Columbia holds a scroll (probably the Constitution) and an American flag.|Entered . . . 1859 by Lewis Dela . . . Pennsylvania.|Lewis N. Rosenthal Lith. Phila.|Philadelphia, Lee & Walker, 722 Chestnut Street.|The Library's copy of the music cover was deposited for copyright on September 15, 1859.|Title appears as it is written on the item.|Published in: American political prints, 1766-1876 / Bernard F. Reilly. Boston : G.K. Hall, 1991, entry 1859-2.
Poster showing Liberty shaking the hand of a sailor. Printed by the U.S. Navy Publicity Bureau, 318 W. 39th St., N.Y. The U.S. Navy Publicity Bureau gratefully acknowledges its indebtedness to Mr. J.C. Leyendecker for this design and to the Beck Engraving Co. for the reproduction.
Poster showing workers against a background of smokestacks. Committee on Public Information, Division of Pictorial Publicity.
Poster showing a figure on a galloping horse, carrying a torch, charging between a worker with tools and a warrior in armor with sword and shield. Caption in Russian: "Year 1914," with additional Russian text. Forms part of: Willard and Dorothy Straight Collection.
Poster showing a soldier on horseback carrying a Russian flag. Signed in Cyrillic: A. O. Maksimov. Caption in Russian: "Military loan." Caption: This is the only American ambulance now saving lives in Russia. Send contributions to 527 Fifth Avenue, Room 501, New York. Forms part of: Willard and Dorothy Straight Collection.
Poster showing an ambulance on a battlefield, with Russian men standing in foreground. Caption: This is the only American ambulance now saving lives in Russia. Send contributions to The American Ambulance in Russia, 527 Fifth Avenue, New York City. Forms part of: Willard and Dorothy Straight Collection.
Poster showing soldiers advancing with bayonnets extended. Caption in Russian: "Military 5 1/2 % bonds." Poster has been trimmed and pasted into irregular shape. Forms part of: Willard and Dorothy Straight Collection.