This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Individuals with metabolic syndrome have a 2-fold increased risk of cardiovascular disease, but few strategies provide adequate cardiovascular risk reduction for this group. One option to lower this risk is to reduce atherogenic lipids, particularly low-density lipoprotein cholesterol. Statins are a recommended first-line therapy for this purpose, but this approach doesn’t always provide sufficient LDL-C lowering to optimally reduce cardiovascular risk. Now, researchers have shown that alirocumab, a proprotein converstase subtilisin/kexin type 9 inhibitor, or PCSK9 inhibitor, approved for LDL-C reduction, may address this need. Pooled clinical trial data from ten phase 3 clinical trials from the ODYSSEY clinical development program showed alirocumab significantly lowered LDL-C in individuals both with and without metabolic syndrome..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Alirocumab, a drug that inhibits PCSK9 and helps clear the blood of atherogenic lipids, may be of benefit for individuals with type 2 diabetes who are most at risk of cardiovascular disease. According to the International Diabetes Federation, heart disease is the leading cause of death among people with type 2 diabetes. One factor that might contribute to that grim statistic is the high mixed dyslipidemia prevalence in this population. Mixed dyslipidemia is characterized by elevated triglycerides, and hence high triglyceride-rich lipoprotein, or remnant cholesterol, and high cholesterol levels; and low serum levels of high-density lipoprotein cholesterol, or HDL-C. Despite treatment with statins and other lipid-lowering therapies targeting atherogenic lipoproteins, management of mixed dyslipidemia remains challenging, especially among individuals with diabetes..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"A recent analysis suggests that ixazomib, an oral proteasome inhibitor (or PI), is tolerable and enhances therapeutic responses in patients with multiple myeloma. Ixazomib is approved for use in combination with lenalidomide and dexamethasone for patients who have already received 1 or more prior therapy. The promising results obtained for non-transplant patients taking ixazomib alone, if their disease has responded to primary induction therapy, point to a new possible treatment option for multiple myeloma. Multiple myeloma is a form of cancer that develops in bone marrow. Here, the body normally generates white blood cells that help fight off infection. But in multiple myeloma, malignant cells gradually crowd out these disease-fighting cells, compromising the body’s immune response, while also damaging the bones. The malignant cells also secrete large amounts of a non-functional protein which leads to kidney failure and other harms..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

"Babies and young children are like the R&D division of the human species," says psychologist Alison Gopnik. Her research explores the sophisticated intelligence-gathering and decision-making that babies are really doing when they play.

The properties of organic molecules depend on the structure, and knowing the names of organic compounds allow us to communicate with other chemists. We'll be learning about different aspects of molecular structure, including common functional groups and conformations.

Poster showing Uncle Sam with a truck full of citizens holding Liberty Bonds. The truck bears a sign, "To Berlin." United Cigars.

This resource provides detailed information on how to cite and write in APA style. Writers will learn how to organize their work and develop in-text and formal reference lists according to APA.

Studied students stupefy! Students learn about alliteration by listening to an alliterative read-aloud and apply the knowledge they gain to the creation of their own poem and illustration.

Short Description:
This book explores the topic of anxiety disorders. Including information on neuroscience, assessment, and intervention.

Long Description:
Anxiety disorders are one of the most common mental health disorders experienced by people in the United States. However, given their complexity, they are also one of the most misunderstood. While these disorders can be quite debilitating, appropriate assessment, diagnosis, and treatment planning are critical to the recovery process.

The chapters introduce the reader to a variety of topics. The chapters include introduction to anxiety and the nervous system, building blocks of anxiety, assessing anxiety, and cognitive and behavioral interventions. The chapters were written to build upon one another. Thus, skipping a chapter and jumping ahead can be problematic as the reader may have missed foundational material in the prior chapters.

I would like to acknowledge that as part of this open educational resource product, there were several mental health providers that peer-reviewed these chapters. I would like to extend a deep gratitude for their time, edits, and constructive feedback.

Word Count: 20017

(Note: This resource's metadata has been created automatically by reformatting and/or combining the information that the author initially provided as part of a bulk import process.)

This animation depicts the carbon cycle in a fashion that is suited for younger audiences. The video discusses how carbon enters and exits the environment through both natural and human-driven ways.

"Normally, an animal gets half its DNA from its mother and half from its father. But Dolly had three mothers: one mother gave Dolly her DNA; one supplied an egg; and the third, her surrogate mother, gave birth to her. Dolly is an identical twin of the mother who gave her her DNA. But Dolly is six years younger."This kid-friendly Web page helps kids understand how and why Dolly was cloned, and understand the potential benefits of cloning as well as the controversy it raises.

Join Simon, Anita, Emily and the rest of Ms. Patel's class as they gain an understanding of how the Earth works as a system while preparing their end of the school year play.

In this informational text, elementary school readers learn about the difference between weather and climate and about components of the climate system. The text can be used to practice visualizing and other comprehension strategies. Available in K-2 and 3-5 grade bands and as an illustrated book as well as a text document, the story appears in the online magazine Beyond Weather and the Water Cycle.

Have you ever wondered what defines a gemstone? Or, maybe you have a favorite and want to know how it's formed. No matter what the reason is, this resource was created to help you learn more about gemstones! This resource includes facts about rubies, sapphires, emeralds, tanzanite, opals, and diamonds including where they are formed, how they are formed, colors for each, and more! Then test your new knowledge with a quiz! Student OER: Jessica Brown, Author 

This article provides an overview of icebergs' formation and characteristics and the hazards associated with icebergs.

In this lesson plan, the traditional autobiography writing project is given a twist as students write alphabiographies—recording an event, person, object, or feeling associated with each letter of the alphabet. Students are introduced to the idea of the alphabiography through a presentation giving the instructions of how to create guidelines for writing their own alphabiographies. Students create an entry for each letter of the alphabet, writing about an important event from their lives. After the entry for each letter, students sum up the stories by writing the life lessons they learned from the events. Since this type of autobiography breaks out of chronological order, students can choose what has been important in their lives. And since the writing pieces are short, even reluctant writers are eager to write!