(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

Physical examination showed normal vital signs. There was no difficulty breathing, chest pain, or headache. Neurologic evaluation demonstrated an awake and alert, right-handed female oriented to person, place, and time. She was noted to have persistent word finding difficulty and was unable to name a pen and a watch. At the time of neurological testing, the patient's motor and sensory function had essentially returned to normal. Cranial nerves were intact bilaterally and deep tendon reflexes were symmetric and slightly reduced. Her gait was unremarkable and Romberg testing was negative.

(This case study was added to OER Commons as one of a batch of over 700. It has relevant information which may include medical imagery, lab results, and history where relevant. A link to the final diagnosis can be found at the end of the case study for review. The first paragraph of the case study -- typically, but not always the clinical presentation -- is provided below.)

The patient started early intervention shortly after the onset of symptoms, but therapies were limited due to his oppositional behaviors. After evaluation by a developmental pediatrician, he did not meet diagnostic criteria for autism spectrum disorder. The physical exam was unremarkable, an audiology test was normal, and a brain MRI showed no evidence of focal parenchymal abnormality. Given the patient's medical history, global developmental delays, behavioral issues, as well as a family history of a maternal uncle with brain malformation and similar behavioral issues further genetic testing was undertaken. SNP micro-array analysis was negative for copy number alterations. FMR1 gene mutation analysis by PCR for Fragile X Mental Retardation is shown in Figure 1.

The Pedro Albizu Campos Digital Resource Collection contains digitized images of all of the archival documents of Pedro Albizu Campos maintained by Harvard University Archives (HUA). The collection focuses on 1912-1923 (the date of Albizu’s official Harvard Law School degree conferral). The digital images are of every single document of Pedro Albizu Campos from the University of Vermont, Harvard College, and Harvard Law School. It includes newspaper clippings in Albizu’s alum file and Laura Meneses del Carpio, wife of Albizu, maintained by Radcliffe College. The collection includes Spanish translations of most digital images and English text for most handwritten letters and notes.

This lesson is part of Software Carpentry workshops and teach an introduction to plotting and programming using python. This lesson is an introduction to programming in Python for people with little or no previous programming experience. It uses plotting as its motivating example, and is designed to be used in both Data Carpentry and Software Carpentry workshops. This lesson references JupyterLab, but can be taught using a regular Python interpreter as well. Please note that this lesson uses Python 3 rather than Python 2.

This resource provides lecture notes and writing assignments for the study of poetry. While specific poems are presented here, these notes and assignments can be adapted and applied to practically any thematic group of poems.  The unit contains several modules. The first posits the work of African American poet Langston Hughes as poems that establish a legacy of oratorical poems addressing social issues faced not only by African Americans, but by any and all Americans, especially the historically disenfranchised.  The unit explores poems in Hughes' legacy, focusing on three poems by African American poets Maya Angelou, Elizabeth Alexander, and Amanda Gorman, who composed U.S. presidential inaugural poems. The second module explores nature poetry. Students read and analyze poems that explore, ponder and sometimes celebrate the relationship between human beings and nature. Ultimately, students compose poetry explication essays. The third module explores the book-length prose poem "I Remember" (Joe Brainard), teaching students to locate and make use of peer-reviewed articles.  Additionally, students write their own "I Remember" poems. Included are introductory lecture, discussion , short writing, explication , and several other assignments. Unless otherwise noted, the materials in this unit are licensed under CC BY-NC-SA.

This course provides a thorough introduction to the C programming language, the workhorse of the UNIX operating system and lingua franca of embedded processors and micro-controllers. The first two weeks will cover basic syntax and grammar, and expose students to practical programming techniques. The remaining lectures will focus on more advanced concepts, such as dynamic memory allocation, concurrency and synchronization, UNIX signals and process control, library development and usage. Daily programming assignments and weekly laboratory exercises are required. Knowledge of C is highly marketable for summer internships, UROPs, and full-time positions in software and embedded systems development.

The course introduces formal theories of context-dependency, presupposition, implicature, context-change, focus and topic. Special emphasis is on the division of labor between semantics and pragmatics. It also covers applications to the analysis of quantification, definiteness, presupposition projection, conditionals and modality, anaphora, questions and answers.

The evidence-based community has championed the public registration of pre-analysis plans (PAPs) as a solution to the problem of research credibility, but without any evidence that PAPs actually bolster the credibility of research. We analyze a representative sample of 195 pre-analysis plans (PAPs) from the American Economic Association (AEA) and Evidence in Governance and Politics (EGAP) registration platforms to assess whether PAPs are sufficiently clear, precise and comprehensive to be able to achieve their objectives of preventing “fishing” and reducing the scope for post-hoc adjustment of research hypotheses. We also analyze a subset of 93 PAPs from projects that have resulted in publicly available papers to ascertain how faithfully they adhere to their pre-registered specifications and hypotheses. We find significant variation in the extent to which PAPs are accomplishing the goals they were designed to achieve

This article with practical instructions about using Fast Plants in undergraduate research experiences was published as an addendum to a workshop given at the 2017 ABLE Conference in Madison, WI. Contains ideas for helping students at high school and undergraduate levels to conduct independent research. Published in Tested Studies for Laboratory Teaching Proceedings of the Association for Biology Laboratory Education Volume 39, Article 11, 2018

El libro "Principios Básicos de Bioquímica para Agroecología" es una obra que busca proporcionar a los estudiantes de esta disciplina una base sólida en los fundamentos de la bioquímica, escrita por un equipo de docentes investigadores, se presenta como un recurso didáctico para aquellos estudiantes que buscan comprender la relación entre la química, la bioquímica y la agricultura, iniciando con la definición conceptual de bioquímica. A medida que avanza el texto, se profundiza en los conceptos de estructuras de la célula vegetal, sus características y funciones, así como también se describen las proteínas, lípidos, carbohidratos y ácidos nucleicos. Además, aborda temas importantes para la agroecología, como la fotosíntesis y la función de los nutrientes en las plantas. El enfoque en estos temas permite a los estudiantes de agroecología entender cómo los principios de la bioquímica son relevantes para el estudio de la agricultura y la producción de alimentos. Así también incluye una variedad de recursos de apoyo para el aprendizaje, como cuadros, tablas, diagramas y ejemplos. Estos recursos ayudan a los estudiantes a visualizar y comprender los conceptos difíciles de la bioquímica, y a aplicarlos a situaciones del mundo real. Una de las características más destacadas de este documento es su lenguaje accesible y fácil de entender. Los autores han evitado el uso excesivo de terminología técnica y han explicado los conceptos de manera clara y concisa. Esto hace que sea adecuado para estudiantes de diversos niveles y antecedentes académicos. En conclusión, es material bibliográfico valioso y esencial para cualquier estudiante que desee comprender los principios básicos de la bioquímica y su aplicación en el campo de la agroecología. Con una escritura clara, recursos de apoyo útiles y un enfoque en temas relevantes para la agricultura, representa una excelente herramienta para el aprendizaje y la comprensión de la bioquímica y su relación con la producción de alimentos.

Designed to serve Earth Science students non-science majors at the community college level.

The PDF file available here is ideal for creating a print version of the textbook. This textbook offers a pluralistic approach to microeconomic theory, macroeconomic theory, and international economic theory. It adopts a critical approach to neoclassical economics and incorporates heterodox alternatives to mainstream economics throughout the book.

This class covers quantitative analysis of uncertainty and risk for engineering applications. Fundamentals of probability, random processes, statistics, and decision analysis are covered, along with random variables and vectors, uncertainty propagation, conditional distributions, and second-moment analysis. System reliability is introduced. Other topics covered include Bayesian analysis and risk-based decision, estimation of distribution parameters, hypothesis testing, simple and multiple linear regressions, and Poisson and Markov processes. There is an emphasis placed on real-world applications to engineering problems.

Data Carpentry Genomics workshop lesson to learn how to structure your metadata, organize and document your genomics data and bioinformatics workflow, and access data on the NCBI sequence read archive (SRA) database. Good data organization is the foundation of any research project. It not only sets you up well for an analysis, but it also makes it easier to come back to the project later and share with collaborators, including your most important collaborator - future you. Organizing a project that includes sequencing involves many components. There’s the experimental setup and conditions metadata, measurements of experimental parameters, sequencing preparation and sample information, the sequences themselves and the files and workflow of any bioinformatics analysis. So much of the information of a sequencing project is digital, and we need to keep track of our digital records in the same way we have a lab notebook and sample freezer. In this lesson, we’ll go through the project organization and documentation that will make an efficient bioinformatics workflow possible. Not only will this make you a more effective bioinformatics researcher, it also prepares your data and project for publication, as grant agencies and publishers increasingly require this information. In this lesson, we’ll be using data from a study of experimental evolution using E. coli. More information about this dataset is available here. In this study there are several types of files: Spreadsheet data from the experiment that tracks the strains and their phenotype over time Spreadsheet data with information on the samples that were sequenced - the names of the samples, how they were prepared and the sequencing conditions The sequence data Throughout the analysis, we’ll also generate files from the steps in the bioinformatics pipeline and documentation on the tools and parameters that we used. In this lesson you will learn: How to structure your metadata, tabular data and information about the experiment. The metadata is the information about the experiment and the samples you’re sequencing. How to prepare for, understand, organize and store the sequencing data that comes back from the sequencing center How to access and download publicly available data that may need to be used in your bioinformatics analysis The concepts of organizing the files and documenting the workflow of your bioinformatics analysis

Intern Prescot Nelson at Succinct Psychology (Psychcinct), under the guidance of professor Daniel Reynolds, created the entire course series for the Psych2e Openstax textbook. We are allowing everyone to share and embed this resource.

This lesson focuses on the conservation of energy solely between gravitational potential energy and kinetic energy, moving students into the Research and Revise step. Students start out with a virtual laboratory, and then move into the notes and working of problems as a group. A few questions are given as homework. A dry lab focuses on the kinetic and potential energies found on a roller coaster concludes the lesson in the Test Your Mettle phase of the Legacy Cycle.

The topic of this video is energy in general, and specifically the ways we can quantify it. In order to make the concepts accessible to a broad audience, this video focuses on everyday things and events. How is it that energy plays a part in a child riding a scooter? How is the energy we consume in playing related to the energy on the food we eat? This video poses these questions to the class and challenges them to put a list of five such items into an ordering from most energy to least.

Reading list of open/free materials to support Argument, Research and Multimodal Composition course.

Course description:
WR 122 continues the focus of WR 121 in its review of rhetorical concepts and vocabulary, in the development of reading, thinking, and writing skills, along with metacognitive competencies understood through the lens of a rhetorical vocabulary. Specifically, students will identify, evaluate, and construct chains of reasoning, a process that includes an ability to distinguish assertion from evidence, recognize and evaluate assumptions, and select sources appropriate for a rhetorical task. Students will employ a flexible, collaborative, and appropriate composing process, working in multiple genres, and utilizing at least two modalities. They will produce 3500-4500 words of revised, final draft copy or an appropriate multimodal analog for this amount of text. Students will produce at least one essay of a minimum of 1500 words, demonstrating competence in both research and academic argumentation.

The objective of this study was to evaluate the nature and extent of reproducible and transparent research practices in neurology publications. Methods The NLM catalog was used to identify MEDLINE-indexed neurology journals. A PubMed search of these journals was conducted to retrieve publications over a 5-year period from 2014 to 2018. A random sample of publications was extracted. Two authors conducted data extraction in a blinded, duplicate fashion using a pilot-tested Google form. This form prompted data extractors to determine whether publications provided access to items such as study materials, raw data, analysis scripts, and protocols. In addition, we determined if the publication was included in a replication study or systematic review, was preregistered, had a conflict of interest declaration, specified funding sources, and was open access. Results Our search identified 223,932 publications meeting the inclusion criteria, from which 400 were randomly sampled. Only 389 articles were accessible, yielding 271 publications with empirical data for analysis. Our results indicate that 9.4% provided access to materials, 9.2% provided access to raw data, 0.7% provided access to the analysis scripts, 0.7% linked the protocol, and 3.7% were preregistered. A third of sampled publications lacked funding or conflict of interest statements. No publications from our sample were included in replication studies, but a fifth were cited in a systematic review or meta-analysis. Conclusions Currently, published neurology research does not consistently provide information needed for reproducibility. The implications of poor research reporting can both affect patient care and increase research waste. Collaborative intervention by authors, peer reviewers, journals, and funding sources is needed to mitigate this problem.