This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Many patients undergoing chemotherapy for cancer develop a serious side effect called chemotherapy-induced peripheral neuropathy (CIPN). CIPN involves pain, tingling, burning, or numbness in the hands and feet and is caused by neuroinflammation triggered by the protein HMGB1, but the exact mechanisms aren’t clear. To learn more and help find a treatment, researchers recently examined the plasma of human patients and mice with oxaliplatin-induced CIPN. They found that the levels of HMGB1 and its target enzyme MMP-9 (a pain marker) were elevated in CIPN plasma and that a higher dose of oxaliplatin was associated with higher HMGB1 levels and worse pain. In cell experiments, HMGB1 was degraded—and inflammatory molecule expression was suppressed—when the enzyme AMPK was activated suggesting that AMPK activation might be beneficial for CIPN. These effects were dependent on the protein SR-A1..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This is a PBL project that had students design and present to a panel of local experts a set of possible rides for a proposed amusement park as a way for them to master and apply the concepts of rotational motion. It was specifically designed to help students increase their depth of knowledge of angular kinematics, force, energy, and momentum. The project required students to design and then describe in detail one or more amusement park rides that would be the basis of authentically demonstrating their depth of knowledge for these topics. Note that the project was designed and delivered per the North Carolina honors Physics curriculum and it can be customized to meet your own specific curriculum needs and resources.

Students design, build and test model roller coasters using foam tubing. The design process integrates energy concepts as they test and evaluate designs that address the task as an engineer would. The goal is for students to understand the basics of engineering design associated with kinetic and potential energy to build an optimal roller coaster. The marble starts with potential energy that is converted to kinetic energy as it moves along the track. The diameter of the loops that the marble traverses without falling out depends on the kinetic energy obtained by the marble.

In October 2020, Amy Coney Barrett became the fifth woman confirmed to the U.S. Supreme Court.

This resource is from a collection of biographies of famous women. It is provided by the National Women's History Museum, and may include links to supplemental materials including lesson plans about the subject and related topics, links to related biographies, and "works cited" pages. The biographies are sponsored by Susan D. Whiting.

This patient education program explains amyotrophic lateral sclerosis (ALS or Lou Gehrig's Disease) including the causes, symptoms, diagnosis and treatment options. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute.

A Cartilha Eletrônica de Educação Ambiental sobre Resíduos Sólidos “ANA LAURA POR UM MUNDO SUSTENTÁVEL”de autoria de Elane Alvarenga Oliveira Hora e Rosana de Oliveira Santos Batista, trata-se de um Produto Técnico Educacional apresentado ao Programa de Pós-Graduação em Rede Nacional para o Ensino das Ciências Ambientais - PROFCIAMB, Universidade Federal de Sergipe - UFS, para atender aos requisitos do Mestrado Profissional para a obtenção do título de Mestre em Ciências Ambientais. A cartilha é um importante instrumento de referência de Educação Ambiental, pois esse material didático de divulgação será utilizado para dar apoio e também sensibilizar os gestores ambientais municipais, coordenadores e equipe das Novas Salas Verdes, assim como, de seu público alvo, ou seja, alunos da Educação Básica, a comunidade em geral e demais municípios sergipanos sobre os impactos e problemáticas socioambientais relacionadas à temática de resíduos sólidos em Sergipe, em conformidade com a Política Nacional de Resíduos Sólidos Lei 12.305/2010 (BRASIL, 2010).

Ana Roqué de Duprey, a prolific educator, writer, and scientist, founded the first woman’s suffrage organization in Puerto Rico in 1917.

This resource is from a collection of biographies of famous women. It is provided by the National Women's History Museum, and may include links to supplemental materials including lesson plans about the subject and related topics, links to related biographies, and "works cited" pages. The biographies are sponsored by Susan D. Whiting.

3-part lecture series given at Kwame Nkrumah University of Science and Technology about infections with Gram-negative obligate anaerobes

Because small mammals are prey species, they do not take to intensive conditions of surgery and hospitalisation very readily. Those that are handled very frequently by their owners are more bonded with humans and better surgical subjects as a result. Rodents and rabbits are particularly susceptible to the surgical complications of dehydration (blood and fluid loss), core temperature depression, hypovolaemic shock, ileus and renal and respiratory depression.

Este es un libro que pretende presentar de manera muy básica los sonidos del español con audios y ejercicios para practiar.

An introductory course in analog circuit synthesis for microelectronic designers. Topics include: Review of analog design basics; linear and non-linear analog building blocks: harmonic oscillators, (static and dynamic) translinear circuits, wideband amplifiers, filters; physical layout for robust analog circuits; design of voltage sources ranging from simple voltage dividers to high-performance bandgaps, and current source implementations from a single resistor to high-quality references based on negative-feedback structures.

This problem illustrates how numerical theories are developed, how we might test this theory with an analog model, and how numerical models are constructed and the limitations of numerical modeling.

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This lesson follows the NGSS standards for reviewing analog and digital waves. Students will be able to review the differences and similarities of analog and digital waves. Students will also be able to review how signals sent as analog or digital waves are used. 

This lesson follows the NGSS standards for reviewing analog and digital waves. Students will be able to review the differences and similarities of analog and digital waves. Students will also be able to review how signals sent as analog or digital waves are used. 

Ce document détaille la démarche de l’analyse ACV.la lecture de ce document permet de découvrir les domaines d’application de la méthode ACV et d'appréhender les avantages et les inconvénients de l’analyse.A la fin de la lecture, l'apprenant sera capable de Maitriser les outils d’analyse des impacts.