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Advanced exploration of the ecological consequences of trophic downgrading in mixed/short grass prairies in North America
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CC BY-NC-SA
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North American ecosystems have fundamentally changed over the late Pleistocene and Holocene; from a system dominated by mammoths, to bison, to domestic livestock. Given the very different body size and herd formation of these 'ecosystem engineers', it is likely that animals influence soil structure, water tables, vegetation and other animals in the ecosystems. What has been the ecological influence of the continued 'downsizing' of the largest animals in the ecosystem?

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Subject:
Applied Science
Biology
Environmental Science
History
Information Science
Life Science
Mathematics
Measurement and Data
Material Type:
Activity/Lab
Provider:
Science Education Resource Center (SERC) at Carleton College
Provider Set:
Teach the Earth
Author:
Dennis Ruez
Date Added:
09/26/2022
The African Americans: Many Rivers to Cross
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Educational Use
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Noted Harvard scholar Henry Louis Gates, Jr. recounts the full trajectory of African-American history in his groundbreaking series The African Americans: Many Rivers to Cross. The series explores the evolution of the African-American people, as well as the multiplicity of cultural institutions, political strategies, and religious and social perspectives they developed — forging their own history, culture and society against unimaginable odds.

Using video clips from The African Americans: Many Rivers to Cross, this collection of lesson plans addresses a wide range of themes of the African-American experience from 1500 to the present.

Subject:
History
U.S. History
Material Type:
Activity/Lab
Lesson
Module
Primary Source
Provider:
PBS LearningMedia
Author:
The WNET Group
Date Added:
01/30/2023
Agarose gel electrophoresis
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CC BY-NC-SA
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In this module, students prepare and run an agarose gel that they use to separate DNA molecules of various sizes. Students stain the gels with ethidium bromide to visualize the positions of DNA molecules. Students estimate the sizes of separated DNA molecules by their migration distances relative to those of molecular weight standards. This module is part of a semester-long introductory lab class, Investigations in Molecular Cell Biology, at Boston College. 

Subject:
Biology
Chemistry
Material Type:
Module
Author:
Clare OConnor
Date Added:
08/29/2018
The Airplane Graveyeard
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During World War Two, a fierce battle between American and Japanese forces on Kwajalein atoll left a trail of debris on the deep lagoon floor. This lagoon now has one of the largest collections of well-preserved aircraft in the world. In this video, as part of the first ever film crew allowed onto this secret military base, Jonathan explores a B-25, F4-U Corsair and Dauntless dive bomber still sitting on the bottom of the ocean, as if ready to take off. Please see the accompanying study guide for educational objectives and discussion points.

Subject:
Oceanography
Physical Science
Material Type:
Diagram/Illustration
Lesson Plan
Provider:
Jonathan Bird's Blue World
Provider Set:
Jonathan Bird's Blue World
Author:
Jonathan Bird Productions
Oceanic Research Group
Date Added:
03/01/2007
All About Cloning
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"Normally, an animal gets half its DNA from its mother and half from its father. But Dolly had three mothers: one mother gave Dolly her DNA; one supplied an egg; and the third, her surrogate mother, gave birth to her. Dolly is an identical twin of the mother who gave her her DNA. But Dolly is six years younger."This kid-friendly Web page helps kids understand how and why Dolly was cloned, and understand the potential benefits of cloning as well as the controversy it raises.

Subject:
Biology
Genetics
Life Science
Material Type:
Reading
Provider:
American Museum of Natural History
Provider Set:
American Museum of Natural History
Date Added:
02/16/2011
Allele frequency
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CC BY-NC-SA
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Allele frequencies in populations and how they differ from genotype frequencies. Created by Sal Khan.

Subject:
Biology
Life Science
Material Type:
Lesson
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Sal Khan
Date Added:
06/23/2014
All in the Family
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Educational Use
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In this Evolution Web feature, test your skills at judging who's who on the tree of life while you learn about the tools and methods of cladistics.

Subject:
Life Science
Material Type:
Activity/Lab
Interactive
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
Clear Blue Sky Productions
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Allopatric Speciation
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Educational Use
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These images from the Smithsonian Institution depict Nancy Knowlton's work with snapping shrimp in Panama. Knowlton found that the closing of the isthmus -- dividing the Pacific Ocean from the Caribbean -- resulted in new species of shrimp.

Subject:
Geoscience
Life Science
Physical Science
Material Type:
Diagram/Illustration
Reading
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Alzheimer's Disease
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Educational Use
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This video segment from the Secret of Life School Video: "Genetic Medicine: Tinkering with Our Genes" explores the potential for gene therapy to cure diseases like Alzheimer's.

Subject:
Life Science
Material Type:
Activity/Lab
Provider:
PBS LearningMedia
Provider Set:
PBS Learning Media: Multimedia Resources for the Classroom and Professional Development
Author:
National Science Foundation
WGBH Educational Foundation
Date Added:
09/26/2003
Alzheimer’s disease offers clues to fighting brain cancer
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CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"Glioma is the most common and lethal form of brain cancer. Among patients with the highest grade of glioma, fewer than 6% survive up to 5 years after diagnosis. Interestingly, glioma is extremely rare in one large population of patients patients with Alzheimer’s disease. That suggests that an anti-glioma molecule could play a critical role in the development of Alzheimer’s. In a recent study, researchers assessed one possible candidate: presenilin-1. Presenilin-1 is a protein that assists the formation of amyloid beta, the main component of the hallmark plaques found in the brains of patients with Alzheimer’s. Experiments showed that high presenilin-1 levels in glioma tissue from patients correlated with low tumor proliferation. Closer examination revealed that presenilin-1 kept cancer from spreading by preventing tumor cells from replicating their DNA. This mechanism could explain the poor prognosis of glioma patients with low levels of presenilin-1..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/24/2020
Alzheimer’s treatment may be more effective for people at highest risk
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"There may be a silver lining for those at high risk for Alzheimer’s: as the chance of getting the disease goes up, certain treatments may become more effective. The risk of developing Alzheimer’s largely relies on a gene called APOE, with different variants conferring more or less risk. Usually, having a high-risk allele is bad news, but a group of researchers from New York University has reported that carrying the high-risk allele could actually boost responsiveness to immunotherapy, a promising new treatment option. The APOE gene helps determine how much beta-amyloid accumulates in the brain. Beta-amyloid starts as small misfolded bits of protein that clump together to form the plaques that are the hallmark of Alzheimer’s. As the plaques appear, the brain deteriorates, particularly in regions associated with memory. One way to potentially halt this process is to use antibodies that recognize beta-amyloid. The antibodies bind to the protein and signal to the immune system to clear it out..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Genetics
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
11/20/2020
American Chestnut Tree
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Educational Use
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This annotated slideshow adapted from KET's Electronic Field Trip to the Forest illustrates how blight decimated the American chestnut tree and the methods scientists use to identify and pollinate the remaining trees to create blight-resistant trees.

Subject:
Ecology
Forestry and Agriculture
Genetics
Geoscience
Life Science
Physical Science
Material Type:
Interactive
Reading
Provider:
PBS LearningMedia
Provider Set:
Teachers' Domain
Author:
KET
The William and Flora Hewlett Foundation
Date Added:
08/25/2008
Analysing linkage disequilibrium with Ensembl
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CC BY
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The Ensembl project offers integrated genome, variation, gene regulation and comparative genomics data of mainly vertebrate genomes on an open access web browser platform.

This webinar will introduce you to the analysis of Linkage Disequilibrium (LD) between variants with Ensembl. We will look at different ways to explore and visualise LD in the Ensembl genome browser website. We will discuss the new LD Calculator tool which has been released with Ensembl 91 and show how to use it.

Who is this course for?
This webinar is aimed at individuals who wish to learn more about analysing LD with Ensembl. No prior knowledge of bioinformatics is required, but an understanding of undergraduate level genetics would be useful.

Outcomes
By the end of the webinar you will be able to:

Analyse linkage disequilibrium between variants in Ensembl
Visualise linkage disequilibrium using the Ensembl Genome Browser

Subject:
Applied Science
Life Science
Material Type:
Lecture
Provider:
EMBL-EBI
Date Added:
03/21/2018
Analysis of “Multimedia and Interactive Tools”
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CC BY-NC-SA
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This document presents the results of the Erasmus+ "InterMedia Project," focusing on the exploration of multimedia and interactivity in the context of education and learning. The first section provides an overview of multimedia, including its definition, origins, evolution, and significance in daily life. The following section delves into the concept of interactivity, defining it and highlighting its different types and importance. The document then explores the added value of multimedia and interactive learning content for learners, training providers, and adult education organizations. It emphasizes the benefits and considerations associated with different age groups of adults. The subsequent section analyses various tools used in the project, such as Animaker, Canva, Exe-learning, HTML Validator, Padlet, the H5P Framework, ThingLink, Powtoon, and W3Schools. Lastly, the document provides information about the project partners, including AJITER, EUPHORIANET, BRAINLOG, and EUROPÄISCHE BILDUNGSINITIATIVE EBI/EIE.

Overall, the Erasmus+ "InterMedia Project" offers valuable insights into the potential of multimedia and interactivity in the field of education.

Subject:
Education
Material Type:
Teaching/Learning Strategy
Author:
Cristina Ceccarelli
Diyana Todorova
Peter Mazohl
Date Added:
05/28/2023
Analysis of the anaerobic digestion metagenome under prophage-inducing stressors
Unrestricted Use
CC BY
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This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"In the absence of oxygen, some prokaryotes can degrade organic matter via anaerobic digestion. This occurs in natural settings, like wetlands, and industrial ones, like wastewater treatment or biogas production. But what about viruses? Bacteriophages can impact their hosts’ community structure through selective pressure and have been used to influence microbial communities, such as through pathogen control. A recent study examined the virome of anaerobic digestion communities undergoing prophage- inducing environmental stresses. The virome was almost entirely composed of tailed bacteriophages of the order Caudovirales. Metagenome reconstruction revealed 1,092 viral genomes and 120 prokaryotic genomes, and over half of the prokaryotic genomes contained a provirus in their genomic sequence. In general, species of viruses and prokaryotes could be grouped by having similar reactions to stressors. Archaea had the most pronounced reactions to stressors and featured behaviors unique to those species..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

Subject:
Biology
Life Science
Material Type:
Diagram/Illustration
Reading
Provider:
Research Square
Provider Set:
Video Bytes
Date Added:
04/14/2023