Only around 0.2-2.0% of the patient population will have detectable RBC antibodies -- fewer still will have multiplePatients more frequently exposed to RBC antigens are more likely to have antibodies (multiply transfused sickle cell adult patients ~47%)So you've mastered the type & screen and antibody panels... but what do you do if an antibody panel is inconclusive?Selected Cell Panels - select cells with minimal overlap of antigens; helpful for patients with a known history of an antibodyEnzyme-treated panels - destroy certain antigens and enhance expression of others; modify RBC surface by removing sialic acid residues and by denaturing or removing glycoproteinsExamples: ficin, papain, bromelin, trypsinOne-step enzyme method: enzymes utilized in place of enhancement media (instead of LISS or PEG)Two-step enzyme method: panel RBCs are treated with an enzyme first, then the antibody ID panel is done with treated cells; should compare reactivity to antibody ID panel of same cells without enzyme treatmentA special case seen in blood banking: Daratumumab ("Dara") patientsDaratumumab is a drug used in treatment of Multiple MyelomaPlasmacytoma or plasma cell cancer - plasma cells express CD 38~30k new cases, ~12.5k deaths per yearAnemia is a key symptom (with calcium levels, renal insufficiency, bone lesions)CD 38 is a cyclic ADP ribose hydrolase - with roles in calcium signalling & NAD metabolismExpressed on all cell types: notably Plasma cells and RBCsOne option for treating Multiple Myeloma is the drug Daratumumab: a monoclonal antibody IgG1K anti-CD 38; kills myeloma cells through patient's own immune responseWhat does this have to do with blood bank?CD38 is found on RBCs -- including screen and panel cells, in crossmatchesDara patients show PANAGGLUTINATION in all AHG testing - positive screen, panel, crossmatch, variable/weak positive DAT (at IgG)Multiple myeloma patients need frequent transfusions - increased chance of developing alloAbEnzyme treated panel case studyDara patient case study

Students are guided through an informal exploration of nonfiction texts and child-oriented Websites, learning browsing and skimming techniques for the purpose of gathering interesting information.

Good morning students, This is a model reading for you. Use it and prepare well.

A folding comic puzzle in which the heads of Confederate General P.G.T. Beauregard and a donkey switch bodies. An example of mass of anti-Beauregard material published in the north after the outbreak of hostilities leading to Civil War.|Published by Samuel Upham, 310 Chestnut Street, Philadelphia. Entered according to Act of Congress, in the year 1861, by Samuel C. Upham, 310 Chestnut St., Philadelphia, in the Clerk's Office of the District Court of the United States, in and of the Eastern District of Pennsylvania.|Title appears as it is written on the item.|Forms part of: American cartoon print filing series (Library of Congress)

This collection uses primary sources to explore The Adventures of Huckleberry Finn by Mark Twain. Digital Public Library of America Primary Source Sets are designed to help students develop their critical thinking skills and draw diverse material from libraries, archives, and museums across the United States. Each set includes an overview, ten to fifteen primary sources, links to related resources, and a teaching guide. These sets were created and reviewed by the teachers on the DPLA's Education Advisory Committee.

Humor, trouble, and adventure follow Tom Sawyer everywhere--from the banks of the Mississippi to the brink of death and back in Mark Twain's first full novel. The Big Read Reader's Guide deepens your exploration with interviews, booklists, timelines, and historical information. We hope this guide and syllabus allow you to have fun with your students while introducing them to the work of a great American author.

Software created by the Eylbid Strategic Partnership co-financed by the Erasmus+ program of the European Union (agreement no. 2019-1-ES01-KA201-064417). This video game can be used as a classroom activity with the following objectives:

to show that language brokering is a common practice that takes place in many schools around the world;
to promote a deeper understanding of what language brokering usually implies for young people;
to present some situations that teachers can analyze and discuss with their students from multiple perspectives as part of reflective practice;
to appreciate multilingualism and raise awareness among young people who translate and interpret in schools;
to provide young language brokers with tools and strategies to express how they feel about language brokering, and thus to take care of emotional health.
The videogame is multilingual and can be played in English, Catalan, German, Italian, and Spanish.

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Programari creat per l'Associació Estratègica Eylbid cofinançada pel programa Erasmus+ de la Unió Europea (acord núm. 2019-1-ES01-KA201-064417). Es tracta d'un videojoc pensat perquè es faci servir com a activitat d'aula amb els objectius següents:

mostrar que la intermediació lingüística és una pràctica comuna que es duu a terme a moltes escoles arreu del món;
promoure una comprensió més profunda del que sol implicar la intermediació lingüística per part dels joves;
presentar algunes situacions que els docents puguin analitzar i discutir amb els seus alumnes des de múltiples perspectives com a part de la pràctica reflexiva;
apreciar el plurilingüisme i sensibilitzar els joves que tradueixen i interpreten a les escoles;
proporcionar als joves intermediaris lingüístics eines i estratègies per expressar com se senten en relació amb la intermediació lingüística i per tenir cura de la salut emocional.
El videojoc té diverses llengües disponibles: alemany, anglès, català, castellà i italià.

 Nebraska Standards: 3.2.2.d, 3.2.1h, 3.2.2.aTarget: Students will review and practice parts of speech, specifically adverbs with self, partners or/and class. When students know how to correctly use adverbs they can enhance thier wrting by making it more interesting, adding details, and using good word choice. Time- 20 minutesMaterials- all optional: paper, pencils, video, partner 

An adverb is a word or an expression that generally modifies a verb, adjective, another adverb, determiner, clause, preposition, or sentence. Adverbs typically express manner, place, time, frequency, degree, level of certainty, etc., answering questions such as how, in what way, when, where, and to what extent.

Students will create an advertisement promoting their chosen form of advertising, including advantages and disadvantages of their form of advertising. These should then be presented to the class to teach the class about their form.

The definition of advertisement is the means of communication in which a product, brand, or service is promoted to customers in order to attract interest, engagement, and sales at times. The attached picture provides the most important techniques that help make a successful advert.

Consumers see or hear thousands of advertisements each day. The April 2017 issue of Page One Economics: Focus on Finance reviews advertising history and strategies ads use to create demand and influence consumer tastes and preferences.

In this activity, students will examine advertisements in French. They will also collaborate to develop an advertising campaign to sell prom tickets at their school. This activity will target all three modes of communication.

Description:                 Advertising Management is a planned managerial process designed to oversee and control the various advertising activities – Here we are going to see an introduction, scope, feature and appeals of advertising, in brief.Learning outcome:           After learning this content, learner can understand the concepts of feature elements, colour scheme, appeal applied in an advertisement

Integrated Marketing Communications (IMC) remain an integral component of marketing. Therefore, understanding how companies effectively communicate and interact with customers (including potential customers) creates the foundation you (student) need to have a firm understanding of how marketing communication manifest in practice which is key to the development of effective marketing skills. Such an understanding will help you succeed in your marketing career. Henceforth, this course is designed to help you start your journey towards your desired entry into marketing careers.

This lesson focuses on teaching students to understand the role of identity in the online marketplace and online advertising, and advertisers’ intent to manipulate consumers.

Pursuing a career in the theater can seem intimidating and overwhelming. In this video from Treasures of New York: The Drama League, students receive advice from successful theater professionals like director Diane Paulus and actress Judith Light. From practical suggestions like staying informed by reading the newspaper, to more general advice like finding one’s passion, students hear from and are inspired by the words of experienced artists.

Students practice discussing advice they would have given themselves in the past. Students will also practice talking about what they would do in a particular situation.