Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

By the end of this section, you will be able to:Identify bacterial diseases that caused historically important plagues and epidemicsDescribe the link between biofilms and foodborne diseasesExplain how overuse of antibiotic may be creating “super bugs”Explain the importance of MRSA with respect to the problems of antibiotic resistance

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"SARS-CoV-2, the virus that causes COVID-19, continues to course through communities around the world. While researchers have learned enough about the virus to build defenses, much remains unknown about how SARS-CoV-2 interacts with the immune system to cause disease. One promising target researchers are exploring is a process known as “T cell exhaustion.” During infection, disease-fighting T cells are recruited to areas where inflammation is taking place. These cells are virus-specific and represent one of the most critical defenses against SARS-CoV-2. Some patients with COVID-19, however, show significantly reduced T cell counts, impairing their ability to fight the disease. Although it’s unclear how T cell exhaustion occurs, numerous potential biomarkers of this process do exist. Among these is the protein PD-1, which helps T cells identify cells as friend or foe..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

During Fall 2021, all MIT students and the general public are welcome to join Professors Richard Young and Facundo Batista as they discuss the science of the COVID-19 pandemic. The livestream of the lectures is available to the public, but only registered students are able to ask questions during the Q&A.
Lectures will be given by leading experts on the fundamentals of coronavirus and host cell biology, immunology, epidemiology, clinical disease, and vaccine and therapeutic development. Guest faculty include Amy Barczak, Dan Barouch, Arup Chakraborty, Victoria Clark, Shane Crotty, Anthony Fauci, Britt Glaunsinger, Salim Karim, Shiv Pillai, Rochelle Walensky, Bruce Walker, Laura Walker, and Andrew Ward.

During Fall 2020, all MIT students and the general public were welcomed to join Professors Richard Young and Facundo Batista as they discussed the science of the pandemic during this new class. The livestream of the lectures was available to the public, but only registered students were able to ask questions during the Q&A. 
Special guest speakers included: Drs. Anthony Fauci, David Baltimore, James Bradner, Victoria Clark, Kizzmekia Corbett, Britt Glaunsinger, Akiko Iwasaki, Eric Lander, Michael Mina, Michel Nussenzweig, Shiv Pillai, Arlene Sharpe, Skip Virgin, and Bruce Walker.
NOTE: This class ran from September 1, 2020 through December 8, 2020.

This course immerses students in the process of building and testing their own digital and board games in order to better understand how we learn from games. We explore the design and use of games in the classroom in addition to research and development issues associated with computer–based (desktop and handheld) and non–computer–based media. In developing their own games, students examine what and how people learn from them (including field testing of products), as well as how games can be implemented in educational settings.

This course is built around practical instruction in the design and analysis of non-­digital games. It provides students the texts, tools, references, and historical context to analyze and compare game designs across a variety of genres. In teams, students design, develop, and thoroughly test their original games to better understand the interaction and evolution of game rules. Covers various genres and types of games, including sports, game shows, games of chance, card games, schoolyard games, board games, and role-­playing games.

This text includes chapters from instructional designers, university faculty and staff, and undergraduate and graduate students, and the text has been divided into three sections to reflect these varied perspectives. Each section begins with research-based perspectives, but also contains more personal narratives at the end. While the context of most of the chapters is the United States, there are also chapters with a Canadian context. It is also important to note that, as of the first half of 2021, the pandemic rages on, and mentions of COVID-19 in the following chapters will be reflective of the state of affairs in North America in the spring and fall of 2020.

This video on HIV in Global Health introduces the student to the origin, and major milestones in the HIV pandemic. Students will learn about scientific breakthroughs in HIV research including important trials. The video also provides insight into public health initiatives to limit the pandemic such as ART programs and different testing strategies. Finally the video sums up future challenges for ending the HIV pandemic.

This resource uses Gholdy Muhammad's Layered Text strategy to pull students into a multimodal lesson providing context for the 1918 Pandemic.

So much has changed since March 2020 when campuses closed. Keeping the doors of learning open we found ways forward and continued to do our learning from home. The world is a different place and being on campus is different too. As you know, campuses are opening in a limited way for 2020-2021 academic year. This short course provides information for ALL students to keep yourself and others safe as a select few go back to campus.Certain links in our module may take you to other websites: We provided these links only as a convenience, and not as an endorsement of any linked site or the information, products or services appearing thereon. These links and sites are not under the control of the creators of this module. If you decide to visit any of these sites, you do so at your own risk. We are not responsible for the content of any such linked sites or any other web page that is not part of our site. Accordingly, you agree that the we will not be responsible or liable in any way for the accuracy, legality, relevancy, decency or copyright compliance of material and information contained in any site linked from this module.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"With the COVID-19 pandemic causing a global health crisis, accurate diagnosis is critical. Diagnosing acute disease relies on RT-PCR tests measuring the presence of SARS-CoV-2 in the sampled material but in patients with suspected COVID-19 with a negative RT-PCR result, measuring anti-viral antibodies can help clinicians identify infected individuals. Antibody testing can also determine if someone was previously infected and help to measure the prevalence of the virus in a community. A new study characterizes an assay measuring total antibodies – combined IgA, IgM, and IgG isotypes – against SARS-CoV-2. The assay, ECLIA, specifically measures antibodies against the S1 subunit of the viral spike, which carries the virus’s receptor binding domain. Researchers in Liechtenstein evaluated ECLIA in a population with 125 cases of confirmed SARS-CoV-2 infection and 1159 individuals without evidence of COVID-19. The results showed a test sensitivity of 97.6%, while the specificity was 99.8%..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The recent outbreak of SARS-CoV-2 infections has strained healthcare systems worldwide and diagnostic testing is a critical part of any pandemic management plan. PCR tests on clinical samples collected by health care professionals (HCPs) is currently the gold standard, but patient self-sampling may facilitate increased testing without adding strain or risk of exposure for HCPs. A recent study tested the sensitivity, feasibility, and acceptance of self-collected oropharyngeal samples. Hospitalized SARS-CoV-2-infected patients collected two self-administered samples and filled out a questionnaire. Researchers also collected HCP-administered samples for comparison. While the HCP-collected samples had the highest estimated sensitivity compared to each of the self-collected samples, at 88%, 78%, and 77% respectively, using both self-collected sample results together increased their estimated sensitivity to 88%, which is comparable to the HCP-collected samples..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This resource is a video abstract of a research paper created by Research Square on behalf of its authors. It provides a synopsis that's easy to understand, and can be used to introduce the topics it covers to students, researchers, and the general public. The video's transcript is also provided in full, with a portion provided below for preview:

"The COVID-19 pandemic, caused by the virus SARS-CoV-2, has spread rapidly since 2019. COVID-19 symptoms are mild in some patients but severe and even life-threatening in others and there are still no reliable treatments for severe COVID-19. In a recent study, researchers investigated the factors related to COVID-19 severity in hospitalized patients with mild or severe illness. Specifically, they investigated the patients’ immune characteristics and signaling pathways involving immune proteins called IFN-Is. Compared with healthy controls, patients with COVID-19 had lower counts of many types of immune cells but higher counts of Th17 cells in their blood and the differences were more drastic in patients with severe disease. In addition, individuals with severe COVID-19 had much lower levels of IFN-I signaling molecules than healthy controls..."

The rest of the transcript, along with a link to the research itself, is available on the resource itself.

This course explores the importance of public transportation to social and economic recovery from the COVID-19 pandemic and seeks to identify approaches to restoring transit ridership, with a focus on Metro Boston. We will attempt to (1) understand whether and how the COVID-19 pandemic can advance sustainable mobility, and specifically the role(s) of public transportation in the COVID-19 recovery process, and (2) identify policies and/or interventions that may encourage pre-COVID transit riders to return to transit and attract net new transit ridership.

This resource is a set of opening qeustions to encourage participants to reflect on the nature of community, especially during times where our normal lives, families, relationships have been disrupted. Phil